Product Name
ADGRE2, Polyclonal Antibody
Full Product Name
ADGRE2 Antibody, HRP conjugated
Product Synonym Names
Adhesion G protein-coupled receptor E2; EGF-like module receptor 2; EGF-like module-containing mucin-like hormone receptor-like 2; CD312; ADGRE2
Product Gene Name
anti-ADGRE2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9UHX3
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human Adhesion G protein-coupled receptor E2 protein (151-323AA)
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-ADGRE2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ADGRE2 antibody
Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Signals probably through G-proteins. Is a regulator of mast cell degranulation (PubMed:26841242).
Product Categories/Family for anti-ADGRE2 antibody
Signal transduction
Applications Tested/Suitable for anti-ADGRE2 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for ADGRE2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001257981.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001271052.1
[Other Products]
UniProt Primary Accession #
Q9UHX3
[Other Products]
UniProt Secondary Accession #
Q8NG96; Q9Y4B1; B4DQ96; E7ESD7; E9PBR1; E9PEL6; E9PFQ5; E9PG91[Other Products]
UniProt Related Accession #
Q9UHX3[Other Products]
Molecular Weight
84,079 Da
NCBI Official Full Name
adhesion G protein-coupled receptor E2 isoform h
NCBI Official Synonym Full Names
adhesion G protein-coupled receptor E2
NCBI Official Symbol
ADGRE2 [Similar Products]
NCBI Official Synonym Symbols
VBU; EMR2; CD312
[Similar Products]
NCBI Protein Information
adhesion G protein-coupled receptor E2
UniProt Protein Name
Adhesion G protein-coupled receptor E2
UniProt Synonym Protein Names
EGF-like module receptor 2; EGF-like module-containing mucin-like hormone receptor-like 2; CD_antigen: CD312
UniProt Gene Name
ADGRE2 [Similar Products]
NCBI Summary for ADGRE2
This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
UniProt Comments for ADGRE2
Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Signals probably through G-proteins. Is a regulator of mast cell degranulation (PubMed:26841242).
Research Articles on ADGRE2
1. Data suggest that blood neutrophils expressing CD11c antigen and EMR2 protein be considered as potential biomarkers for sepsis and systemic inflammatory response syndrome (SIRS), respectively.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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