Full Product Name
CETP Antibody
Product Synonym Names
HDLCQ10 antibody; CETP antibody; BPI fold containing family F antibody; lipid transfer protein I antibody; cholesteryl ester transfer protein antibody; "cholesteryl ester transfer protein; plasma antibody"
Product Gene Name
anti-CETP antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P11597
Specificity
The antibody detects endogenous levels of total CETP protein.
Purity/Purification
Antibodies were purified by antigen-affinity chromatography.
Form/Format
Rabbit IgG in 1XPBS, 1%BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Concentration
1 mg/ml (lot specific)
Immunogen Type
Recombinant Protein
Immunogen Description
Recombinant fragment corresponding to a region within amino acids 4 and 222 of CETP.
Preparation and Storage
Store at -20 degree C
Other Notes
Small volumes of anti-CETP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CETP antibody
Cholesteryl ester transfer protein (CETP) transfers cholesteryl esters between lipoproteins. CETP may effect susceptibility to atherosclerosis. [provided by RefSeq]
Product Categories/Family for anti-CETP antibody
Total protein Ab
Applications Tested/Suitable for anti-CETP antibody
Western Blot (WB)
Application Notes for anti-CETP antibody
Western blotting: 1:500-1:3000
Testing Data of anti-CETP antibody
Sample (30 ug of whole cell lysate) A: HepG2 10% SDS PAGE diluted at 1:500
NCBI/Uniprot data below describe general gene information for CETP. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000069.2
[Other Products]
NCBI GenBank Nucleotide #
NM_000078.2
[Other Products]
UniProt Primary Accession #
P11597
[Other Products]
UniProt Secondary Accession #
Q13987; Q13988; Q53YZ1[Other Products]
UniProt Related Accession #
P11597[Other Products]
Molecular Weight
47,787 Da
NCBI Official Full Name
cholesteryl ester transfer protein isoform 1
NCBI Official Synonym Full Names
cholesteryl ester transfer protein, plasma
NCBI Official Symbol
CETP [Similar Products]
NCBI Official Synonym Symbols
BPIFF; HDLCQ10
[Similar Products]
NCBI Protein Information
cholesteryl ester transfer protein
UniProt Protein Name
Cholesteryl ester transfer protein
UniProt Synonym Protein Names
Lipid transfer protein I
Protein Family
Cholesteryl ester transfer protein
UniProt Gene Name
CETP [Similar Products]
UniProt Entry Name
CETP_HUMAN
NCBI Summary for CETP
The protein encoded by this gene is found in plasma, where it is involved in the transfer of cholesteryl ester from high density lipoprotein (HDL) to other lipoproteins. Defects in this gene are a cause of hyperalphalipoproteinemia 1 (HALP1). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
UniProt Comments for CETP
CETP: Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol. Defects in CETP are the cause of hyperalphalipoproteinemia type 1 (HALP1). Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL). Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Lipid-binding; Secreted; Vesicle
Chromosomal Location of Human Ortholog: 16q21
Cellular Component: extracellular space; extracellular region; vesicle
Molecular Function: lipid transporter activity; phospholipid transporter activity; cholesterol transporter activity; cholesterol binding; phosphatidylcholine binding; lipid binding; triglyceride binding
Biological Process: receptor-mediated endocytosis; cholesterol metabolic process; cholesterol transport; lipid homeostasis; lipoprotein metabolic process; lipid transport; phosphatidylcholine metabolic process; cholesterol homeostasis; reverse cholesterol transport; triacylglycerol metabolic process; phospholipid transport; triacylglycerol transport; transmembrane transport; phospholipid homeostasis
Disease: Hyperalphalipoproteinemia 1
Research Articles on CETP
1. novel atomistic details of the CETP-HDL interaction mechanism
Precautions
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Disclaimer
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