Full Product Name
CETP Antibody
Product Synonym Names
BPIFF; HDLCQ10; CETP
Product Gene Name
anti-CETP antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Purity/Purification
Antigen affinity purification
Concentration
1mg/mL (lot specific)
Immunogen
Recombinant protein of human CETP
Observed Molecular Weight: 55kDa
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-26729 / sc-26731 / sc-25833
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-CETP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CETP antibody
Cholesteryl ester transfer protein (CETP) is a circulating metabolic enzyme that transports cholesterol from the arteries to the liver (1-3). CETP converts cholesteryl esters from antiatherogenic high density lipoproteins (HDLs) to proatherogenic apolipoprotein B (apoB)-containing lipoproteins, including very low-, intermediate-, and low-DLs (3). Efficient transfer and exchange of cholesteryl esters and triglycerides between the lipoprotein classes of human plasma is necessary to maintain healthy arteries (4, 5).
Applications Tested/Suitable for anti-CETP antibody
Western Blot (WB), Immunohistochemistry (IHC)
Western Blot (WB) of anti-CETP antibody
Western blot analysis of extracts of various cell lines, using CETP antibody.
NCBI/Uniprot data below describe general gene information for CETP. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001273014.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001286085.1
[Other Products]
UniProt Secondary Accession #
Q13987; Q13988; Q53YZ1[Other Products]
UniProt Related Accession #
P11597[Other Products]
Molecular Weight
47,787 Da
NCBI Official Full Name
cholesteryl ester transfer protein isoform 2
NCBI Official Synonym Full Names
cholesteryl ester transfer protein, plasma
NCBI Official Symbol
CETP [Similar Products]
NCBI Official Synonym Symbols
BPIFF; HDLCQ10
[Similar Products]
NCBI Protein Information
cholesteryl ester transfer protein; BPI fold containing family F; lipid transfer protein I
UniProt Protein Name
Cholesteryl ester transfer protein
UniProt Synonym Protein Names
Lipid transfer protein I
Protein Family
Cholesteryl ester transfer protein
UniProt Gene Name
CETP [Similar Products]
UniProt Entry Name
CETP_HUMAN
NCBI Summary for CETP
The protein encoded by this gene is found in plasma, where it is involved in the transfer of cholesteryl ester from high density lipoprotein (HDL) to other lipoproteins. Defects in this gene are a cause of hyperalphalipoproteinemia 1 (HALP1). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2013]
UniProt Comments for CETP
CETP: Involved in the transfer of insoluble cholesteryl esters in the reverse transport of cholesterol. Defects in CETP are the cause of hyperalphalipoproteinemia type 1 (HALP1). Affected individuals show high levels of alpha-lipoprotein (high density lipoprotein/HDL). Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Lipid-binding; Secreted, signal peptide; Vesicle
Chromosomal Location of Human Ortholog: 16q21
Cellular Component: extracellular space; extracellular region; vesicle
Molecular Function: lipid transporter activity; phospholipid transporter activity; cholesterol transporter activity; cholesterol binding; phosphatidylcholine binding; lipid binding; triglyceride binding
Biological Process: cholesterol metabolic process; receptor-mediated endocytosis; cholesterol transport; lipid homeostasis; lipoprotein metabolic process; lipid transport; phosphatidylcholine metabolic process; cholesterol homeostasis; triacylglycerol metabolic process; reverse cholesterol transport; phospholipid transport; triacylglycerol transport; transmembrane transport; phospholipid homeostasis
Disease: Hyperalphalipoproteinemia 1
Research Articles on CETP
1. Results suggest the B2B2 genotype of the cholesteryl ester transfer protein TaqIB polymorphism is a protective factor against the development of myocardial infarction.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
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