Inward rectifier potassium channel 13, KCNJ13, ELISA Kit

For Research Use Only. Not for use in diagnostic procedures.

Store at 2 to 8 degree C for 6 months.

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Small volumes of KCNJ13 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS161219 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Inward rectifier potassium channel 13, KCNJ13, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing KCNJ13. The ELISA analytical biochemical technique of the MBS161219 kit is based on KCNJ13 antibody-KCNJ13 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect KCNJ13 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, KCNJ13. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

40,637 Da

potassium voltage-gated channel subfamily J member 13

inward rectifier potassium channel 13

Inward rectifier potassium channel 13

inwardly rectifying K+ channel; may be involved in recycling K+ for the Na+,K(+)-ATPase [RGD, Feb 2006]

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ13 has a very low single channel conductance, low sensitivity to block by external barium and cesium, and no dependence of its inward rectification properties on the internal blocking particle magnesium.

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