Product Name
Glucosidase 2 subunit beta (Prkcsh), Recombinant Protein
Full Product Name
Recombinant Mouse Glucosidase 2 subunit beta (Prkcsh)
Product Gene Name
Prkcsh recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
15-521aa, Full Length of Mature Protein
Sequence
VEVKRPRGVS LSNHHFYEES KPFTCLDGTA TIPFDQVNDD YCDCKDGSDE PGTAACPNGS FHCTNTGYKP LYILSSRVND GVCDCCDGTD EYNSGTVCEN TCREKGRKEK ESLQQLAEVT REGFRLKKIL IEEWKTAREE KQSKLLELQA GKKSLEDQVE TLRAAKEEAE RPEKEAKDQH RKLWEEQQAA AKARREQERA ASAFQELDDN MDGMVSLAEL QTHPELDTDG DGALSEEEAQ ALLSGDTQTD TTSFYDRVWA AIRDKYRSEV PPTDIPVPEE TEPKEEKPPV LPPTEEEEEE EEEPEEEEEE EEEEEEAPPP LQPPQPPSPT EDEKMPPYDE ETQAIIDAAQ EARSKFEEVE RSLKEMEESI RSLEQEISFD FGPSGEFAYL YSQCYELTTN EYVYRLCPFK LVSQKPKHGG SPTSLGTWGS WAGPDHDKFS AMKYEQGTGC WQGPNRSTTV RLLCGKETVV TSTTEPSRCE YLMELMTPAA CPEPPPEAPS DGDHDEL
3D Structure
ModBase 3D Structure for O08795
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Prkcsh recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Prkcsh recombinant protein
This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum (ER). This protein is an acidic phospho-protein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease (PCLD). Alternatively spliced transcript variants encoding distinct isoforms have been observed.
NCBI/Uniprot data below describe general gene information for Prkcsh. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001280579.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001293650.1
[Other Products]
UniProt Primary Accession #
O08795
[Other Products]
UniProt Secondary Accession #
Q921X2[Other Products]
UniProt Related Accession #
O08795[Other Products]
Molecular Weight
59,560 Da
NCBI Official Full Name
glucosidase 2 subunit beta isoform 1
NCBI Official Synonym Full Names
protein kinase C substrate 80K-H
NCBI Official Symbol
Prkcsh [Similar Products]
NCBI Official Synonym Symbols
80K-H; PKCSH
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NCBI Protein Information
glucosidase 2 subunit beta
UniProt Protein Name
Glucosidase 2 subunit beta
UniProt Synonym Protein Names
80K-H protein; Glucosidase II subunit beta; Protein kinase C substrate 60.1 kDa protein heavy chain; PKCSH
Protein Family
Glucosidase
UniProt Gene Name
Prkcsh [Similar Products]
UniProt Synonym Gene Names
PKCSH [Similar Products]
UniProt Comments for Prkcsh
Regulatory subunit of glucosidase II.
Research Articles on Prkcsh
1. TRIM67 regulates Ras signaling via degradation of 80K-H, leading to neural differentiation including neuritogenesis.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
