Full Product Name
Anti-FECH Antibody
Product Gene Name
anti-FECH antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P22830
Species Reactivity
Human, Mouse
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Immunogen
Recombinant protein of human FECH
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-FECH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-FECH antibody
The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway.
Applications Tested/Suitable for anti-FECH antibody
Western Blot (WB)
Application Notes for anti-FECH antibody
WB: 1:500-1:2000
NCBI/Uniprot data below describe general gene information for FECH. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000131.2
[Other Products]
NCBI GenBank Nucleotide #
NM_000140.3
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UniProt Primary Accession #
P22830
[Other Products]
UniProt Secondary Accession #
Q8IXN1; Q8NAN0; A8KA72[Other Products]
UniProt Related Accession #
P22830[Other Products]
Molecular Weight
48,625 Da
NCBI Official Full Name
ferrochelatase, mitochondrial isoform b
NCBI Official Synonym Full Names
ferrochelatase
NCBI Official Symbol
FECH [Similar Products]
NCBI Official Synonym Symbols
EPP; FCE; EPP1
[Similar Products]
NCBI Protein Information
ferrochelatase, mitochondrial
UniProt Protein Name
Ferrochelatase, mitochondrial
UniProt Synonym Protein Names
Heme synthase; Protoheme ferro-lyase
UniProt Gene Name
FECH [Similar Products]
NCBI Summary for FECH
The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.[provided by RefSeq, May 2010]
UniProt Comments for FECH
Catalyzes the ferrous insertion into protoporphyrin IX.
Research Articles on FECH
1. FECH mRNA was largely significantly decreased in colon adenocarcinomas relative to normal colon tissues.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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