B3GNT2, Polyclonal Antibody

N-acetyllactosaminide beta-1; 3-N-acetylglucosaminyltransferase 2 (EC:2.4.1.1493 Publications; B3GNT2; B3GALT7; B3GNT1; Beta-1; 3-N-acetylglucosaminyltransferase 1; BGnT-1; Beta-1; 3-Gn-T1; Beta3Gn-T1; Beta-1; 3-galactosyltransferase 7; Beta-1; 3-GalTase 7; Beta3Gal-T7; Beta3GalT7; b3Gal-T7; Beta-3-Gx-T7; UDP-Gal:beta-GlcNAc beta-1; 3-galactosyltransferase 7; UDP-GlcNAc:betaGal beta-1; 3-N-acetylglucosaminyltransferase 2; BGnT-2; Beta-1; 3-Gn-T2; Beta-1; 3-N-acetylglucosaminyltransferase 2; Beta3Gn-T2; UDP-galactose:beta-N-acetylglucosamine beta-1; 3-galactosyltransferase 7

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

>95%, Protein G Purified

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Small volumes of anti-B3GNT2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains. Shows a marked preference for Gal(beta1-4)Glc(NAc)-based acceptors (PubMed:9892646). Probably constitutes the main polylactosamine synthase.

ELISA (EIA)

45,484 Da

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2

N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

B3GALT7; B3GNT1; BGnT-1; Beta-1,3-Gn-T1; Beta3Gn-T1; Beta-1,3-GalTase 7; Beta3Gal-T7; Beta3GalT7; b3Gal-T7; BGnT-2; Beta-1,3-Gn-T2; Beta-1,3-N-acetylglucosaminyltransferase 2; Beta3Gn-T2  [Similar Products]

B3GN2_HUMAN

This gene encodes a member of the beta-1,3-N-acetylglucosaminyltransferase family. This enzyme is a type II transmembrane protein. It prefers the substrate of lacto-N-neotetraose, and is involved in the biosynthesis of poly-N-acetyllactosamine chains. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2016]

B3GNT2: Catalyzes the initiation and elongation of poly-N- acetyllactosamine chains. Belongs to the glycosyltransferase 31 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; EC 2.4.1.-; Motility/polarity/chemotaxis; Glycan Metabolism - keratan sulfate biosynthesis; Transferase; Cell development/differentiation

Chromosomal Location of Human Ortholog: 2p15

Cellular Component: Golgi membrane; integral to membrane

Molecular Function: galactosyltransferase activity; N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity

Biological Process: axon guidance; carbohydrate metabolic process; cellular protein metabolic process; glycosaminoglycan metabolic process; keratan sulfate biosynthetic process; keratan sulfate metabolic process; O-glycan processing; poly-N-acetyllactosamine biosynthetic process; post-translational protein modification; protein amino acid O-linked glycosylation; sensory perception of smell

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