Full Product Name
SGCE Antibody, FITC Conjugated
Product Synonym Names
Epsilon-sarcoglycan; Epsilon-SG; SGCE; ESG
Product Gene Name
anti-SGCE antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O43556
Purity/Purification
>95%
Protein G Purified
Immunogen
Recombinant Human Epsilon-sarcoglycan protein (8-126AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at-20 degree C or-80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-SGCE antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-SGCE antibody
Signal Transduction
Applications Tested/Suitable for anti-SGCE antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for SGCE. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001092870.1
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NCBI GenBank Nucleotide #
NM_001099400.1
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UniProt Primary Accession #
O43556
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UniProt Secondary Accession #
Q6L8P0; Q75MH8; Q8NFG8; Q8WW28; B2R8N2; D6W5Q8; E9PF60; G5E9K6[Other Products]
UniProt Related Accession #
O43556[Other Products]
Molecular Weight
51,414 Da
NCBI Official Full Name
epsilon-sarcoglycan isoform 3
NCBI Official Synonym Full Names
sarcoglycan epsilon
NCBI Official Symbol
SGCE [Similar Products]
NCBI Official Synonym Symbols
ESG; DYT11; epsilon-SG
[Similar Products]
NCBI Protein Information
epsilon-sarcoglycan
UniProt Protein Name
Epsilon-sarcoglycan
UniProt Gene Name
SGCE [Similar Products]
UniProt Synonym Gene Names
ESG; Epsilon-SG [Similar Products]
NCBI Summary for SGCE
This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. A pseudogene associated with this gene is located on chromosome 2. [provided by RefSeq, Oct 2016]
UniProt Comments for SGCE
Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix.
Research Articles on SGCE
1. The characterization of iPSC-derived cortical neurons with mutations in SGCE revealed that these cells are a suitable model mirroring the endogenous environment in the myoclonus-dystonia patient brain, especially, when focusing on concrete molecular aspects of the disease mechanism.
Precautions
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Disclaimer
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