Full Product Name
AQP2 Antibody, FITC conjugated
Product Synonym Names
Aquaporin-2; AQP-2; ADH water channel; Aquaporin-CD; AQP-CD; Collecting duct water channel protein; WCH-CD; Water channel protein for renal collecting duct; AQP2
Product Gene Name
anti-AQP2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P41181
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human Aquaporin-2 protein (225-271AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-28629 / sc-9880 / sc-9882
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-AQP2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-AQP2 antibody
Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.
Applications Tested/Suitable for anti-AQP2 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for AQP2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000477.1
[Other Products]
NCBI GenBank Nucleotide #
NM_000486.5
[Other Products]
UniProt Primary Accession #
P41181
[Other Products]
UniProt Secondary Accession #
Q9UD68[Other Products]
UniProt Related Accession #
P41181[Other Products]
Molecular Weight
28,837 Da
NCBI Official Full Name
aquaporin-2
NCBI Official Synonym Full Names
aquaporin 2
NCBI Official Symbol
AQP2 [Similar Products]
NCBI Official Synonym Symbols
AQP-CD; WCH-CD
[Similar Products]
NCBI Protein Information
aquaporin-2
UniProt Protein Name
Aquaporin-2
UniProt Synonym Protein Names
ADH water channel; Aquaporin-CD; AQP-CD; Collecting duct water channel protein; WCH-CD; Water channel protein for renal collecting duct
UniProt Gene Name
AQP2 [Similar Products]
UniProt Synonym Gene Names
AQP-2; AQP-CD [Similar Products]
UniProt Entry Name
AQP2_HUMAN
NCBI Summary for AQP2
This gene encodes a water channel protein located in the kidney collecting tubule. It belongs to the MIP/aquaporin family, some members of which are clustered together on chromosome 12q13. Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus. [provided by RefSeq, Oct 2008]
UniProt Comments for AQP2
AQP2: Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Expressed in renal collecting tubules. Belongs to the MIP/aquaporin (TC 1.A.8) family.
Protein type: Channel, misc.; Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, aquaporin family
Chromosomal Location of Human Ortholog: 12q12-q13
Cellular Component: apical plasma membrane; integral to plasma membrane; membrane; plasma membrane
Molecular Function: glycerol channel activity; glycerol transmembrane transporter activity; water channel activity; water transporter activity
Biological Process: cellular water homeostasis; excretion; glycerol transport; renal water homeostasis; water transport
Disease: Diabetes Insipidus, Nephrogenic, Autosomal
Research Articles on AQP2
1. report a novel mutation of the AQP2 gene and highlight an important role of genetic testing for definite diagnosis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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