iron-sulfur cluster scaffold homolog (E. coli), ELISA Kit

Mouse Iron-sulfur cluster assembly enzyme ISCU; mitochondrial (ISCU) ELISA kit; 2310020H20Rik; HML; ISU2; MGC74517; NIFU; NIFUN; hnifU; IscU iron-sulfur cluster scaffold homolog; NifU-like N-terminal domain containing; iron-sulfur cluster assembly enzyme; nitrogen fixation cluster; iron-sulfur cluster scaffold homolog (E. coli)

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of ISCU elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9327411 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the iron-sulfur cluster scaffold homolog (E. coli) (ISCU) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ISCU. The ELISA analytical biochemical technique of the MBS9327411 kit is based on ISCU antibody-ISCU antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ISCU antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ISCU. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

18,098 Da

IscU iron-sulfur cluster scaffold homolog (E. coli)

iron-sulfur cluster assembly enzyme ISCU, mitochondrial; ISCU2; nifU-like protein; NifU-like N-terminal domain containing; nifU-like N-terminal domain-containing protein

Iron-sulfur cluster assembly enzyme ISCU, mitochondrial

Nifun  [Similar Products]

ISCU_MOUSE

ISCU: Involved in the assembly or repair of the [Fe-S] clusters present in iron-sulfur proteins. Binds iron. Defects in ISCU are the cause of myopathy with exercise intolerance Swedish type (MEIS); also known as myopathy with deficiency of succinate dehydrogenase and aconitase or myoglobinuria due to abnormal glycolysis or hereditary myopathy with lactic acidosis (HML). This autosomal recessive metabolic disease is characterized by lifelong severe exercise intolerance, in which minor exertion causes fatigue of active muscles, shortness of breath, and cardiac palpitations in association with lactic acidosis. The biochemical phenotype is characterized by a deficiency in mitochondrial iron-sulfur proteins and impaired muscle oxidative metabolism. Belongs to the NifU family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Mitochondrial

Cellular Component: mitochondrion; cytoplasm; cytosol

Molecular Function: metal ion binding; iron ion binding; iron-sulfur cluster binding; protein complex scaffold

Biological Process: iron-sulfur cluster assembly

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