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AMD1, Polyclonal Antibody

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产品名称: AMD1, Polyclonal Antibody
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简单介绍

AMD1, Polyclonal Antibody


AMD1, Polyclonal Antibody  的详细介绍
Product Name

AMD1, Polyclonal Antibody

Full Product Name

AMD1 antibody - N-terminal region

Product Gene Name

anti-AMD1 antibody

[Similar Products]
Product Synonym Gene Name
ADOMETDC; AMD; DKFZp313L1234; FLJ26964; SAMDC[Similar Products]
Antibody/Peptide Pairs
AMD1 peptide (MBS3236640) is used for blocking the activity of AMD1 antibody (MBS3211692)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Immunogen Sequence
Synthetic peptide located within the following region: MGRMNSDCWY LYTLDFPESR VISQPDQTLE ILMSELDPAV MDQFYMKDGV
OMIM
180980
3D Structure
ModBase 3D Structure for Q5VXN4
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 100%
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human AMD1
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-AMD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
anti-AMD1 antibody
This is a rabbit polyclonal antibody against AMD1. It was validated on Western Blot using a cell lysate as a positive control.

Target Description: The specific function of AMD1 is not yet known.This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Two alternatively spliced transcript variants that encode different proteins have been identified.
Product Categories/Family for anti-AMD1 antibody
Polyclonal; Drugs and Drug Metabolism; Various;
Applications Tested/Suitable for anti-AMD1 antibody
Western Blot (WB)

Western Blot (WB) of anti-AMD1 antibody
WB Suggested Anti-AMD1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: THP-1 cell lysate
anti-AMD1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for AMD1. It may not necessarily be applicable to this product.
NCBI GI #
74275348
NCBI GeneID
262
NCBI Accession #
NP_001028231 [Other Products]
NCBI GenBank Nucleotide #
NM_001033059 [Other Products]
UniProt Primary Accession #
Q5VXN4 [Other Products]
UniProt Related Accession #
P17707[Other Products]
Molecular Weight
21kDa
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NCBI Official Synonym Full Names
adenosylmethionine decarboxylase 1
NCBI Official Symbol
AMD1  [Similar Products]
NCBI Official Synonym Symbols
AMD; SAMDC; ADOMETDC
  [Similar Products]
NCBI Protein Information
S-adenosylmethionine decarboxylase proenzyme
UniProt Protein Name
S-adenosylmethionine decarboxylase proenzyme
Protein Family
S-adenosylmethionine decarboxylase proenzyme
UniProt Gene Name
AMD1  [Similar Products]
UniProt Synonym Gene Names
AMD; AdoMetDC; SAMDC  [Similar Products]
UniProt Entry Name
DCAM_HUMAN
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NCBI Summary for AMD1
This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Multiple alternatively spliced transcript variants have been identified. Pseudogenes of this gene are found on chromosomes 5, 6, 10, X and Y. [provided by RefSeq, Dec 2013]
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Research Articles on AMD1
1. AMD1 mRNA employs ribosome stalling as a mechanism for molecular memory formation
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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