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Dual Oxidase 2 (DUOX2), Polyclonal Antibody

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产品名称: Dual Oxidase 2 (DUOX2), Polyclonal Antibody
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简单介绍

Dual Oxidase 2 (DUOX2), Polyclonal Antibody


Dual Oxidase 2 (DUOX2), Polyclonal Antibody  的详细介绍
Product Name

Dual Oxidase 2 (DUOX2), Polyclonal Antibody

Full Product Name

Biotin-Linked Polyclonal Antibody to Dual Oxidase 2 (DUOX2)

Product Synonym Names
LNOX2; NOXEF2; THOX2; Thyroid oxidase 2; NADH/NADPH thyroid oxidase p138-tox; Dual Oxidase-Like Domains 2; Nicotinamide Adenine Dinucleotide Phosphate Oxidase
Product Gene Name

anti-DUOX2 antibody

[Similar Products]
Matching Pairs
Unconjugated Antibody: Dual Oxidase 2 (MBS2027848)
Biotin Conjugated Antibody: Dual Oxidase 2 (DUOX2) (MBS2094130)
Matching Pairs
Biotin Conjugated Antibody: Dual Oxidase 2 (DUOX2) (MBS2094130)
Immunogen: Dual Oxidase 2 (MBS2028865)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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3D Structure
ModBase 3D Structure for Q8HZK2
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Rat
Concentration
200ug/ml (lot specific)
Conjugation
Biotin
Immunogen
DUOX2 (Asp1229~Phe1517)
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.
Other Notes
Small volumes of anti-DUOX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Applications Tested/Suitable for anti-DUOX2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
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NCBI/Uniprot data below describe general gene information for DUOX2. It may not necessarily be applicable to this product.
NCBI GI #
51889718
NCBI GeneID
397060
NCBI Accession #
NP_999164.2 [Other Products]
NCBI GenBank Nucleotide #
NM_213999.2 [Other Products]
UniProt Primary Accession #
Q8HZK2 [Other Products]
UniProt Secondary Accession #
Q9TT98[Other Products]
UniProt Related Accession #
Q8HZK2[Other Products]
Molecular Weight
175,284 Da
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NCBI Official Full Name
dual oxidase 2
NCBI Official Symbol
DUOX2  [Similar Products]
NCBI Protein Information
dual oxidase 2
UniProt Protein Name
Dual oxidase 2
UniProt Synonym Protein Names
NADH/NADPH thyroid oxidase p138-tox
Protein Family
Dual oxidase
UniProt Gene Name
DUOX2  [Similar Products]
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UniProt Comments for DUOX2
Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
Research Articles on DUOX2
1. G transition of the dual oxidase 2 gene was identified as the causative mutation for a severe congenital hypothyroidism model together with anemia and T lymphopenia which mimics the clinical features of hypothyroid patients">A novel recessive c.1226A>G transition of the dual oxidase 2 gene was identified as the causative mutation for a severe congenital hypothyroidism model together with anemia and T lymphopenia which mimics the clinical features of hypothyroid patients
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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