Product Name
C1 Esterase Inhibitor (SERPING1), Purified Protein
Full Product Name
Human C1 Esterase Inhibitor Depleted Plasma
Product Gene Name
SERPING1 purified protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Other Notes
Small volumes of SERPING1 purified protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for SERPING1 purified protein
HUMAN PLASMA PROTEINS
NCBI/Uniprot data below describe general gene information for SERPING1. It may not necessarily be applicable to this product.
NCBI Accession #
AAM21515.1
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UniProt Secondary Accession #
Q16304; Q547W3; Q59EI5; Q7Z455; Q96FE0; Q9UC49; A6NMU0; A8KAI9; B2R6L5; B4E1F0; B4E1H2[Other Products]
UniProt Related Accession #
P05155[Other Products]
Molecular Weight
55,769 Da[Similar Products]
NCBI Official Full Name
C1 esterase inhibitor
NCBI Official Synonym Full Names
serpin family G member 1
NCBI Official Symbol
SERPING1 [Similar Products]
NCBI Official Synonym Symbols
C1IN; C1NH; HAE1; HAE2; C1INH
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NCBI Protein Information
plasma protease C1 inhibitor
UniProt Protein Name
Plasma protease C1 inhibitor
UniProt Synonym Protein Names
C1 esterase inhibitor; C1-inhibiting factor; Serpin G1
Protein Family
Plasma protease C1 inhibitor
UniProt Gene Name
SERPING1 [Similar Products]
UniProt Synonym Gene Names
C1IN; C1NH; C1 Inh; C1Inh [Similar Products]
UniProt Entry Name
IC1_HUMAN
UniProt Comments for SERPING1
SERPING1: a protein protease inhibitor (C1-inhibitor) that forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play an important role in regulating complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Mutations of the SERPING1 gene is associated with ***** macular degeneration can also cause hereditary angioedema. Binds to E.coli stcE which allows localization of SERPING1 to cell membranes thus protecting the bacteria against complement-mediated lysis. Belongs to the serpin family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 11q12.1
Cellular Component: extracellular region; extracellular space
Molecular Function: protein binding; serine-type endopeptidase inhibitor activity
Biological Process: blood circulation; blood coagulation, intrinsic pathway; negative regulation of complement activation, lectin pathway; platelet degranulation
Disease: Angioedema, Hereditary, Type I; Complement Component 4, Partial Deficiency Of
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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