Product Name
Adrenocorticotropic Hormone (ACTH), Monoclonal Antibody
Full Product Name
PE-Linked Monoclonal Antibody to Adrenocorticotropic Hormone (ACTH)
Product Synonym Names
Endocrinology; Hormone metabolism
Product Gene Name
anti-ACTH antibody
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Matching Pairs
Unconjugated Antibody: Adrenocorticotropic Hormone (ACTH) (MBS2111189)
PE Conjugated Antibody: Adrenocorticotropic Hormone (ACTH) (MBS2107978)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Specificity
The antibody is a mouse monoclonal antibody raised against ACTH. It has been selected for its ability to recognize ACTH in immunohistochemical staining and western blotting.
Purity/Purification
Antigen-specific affinity chromatography followed by Protein A affinity chromatography
Concentration
500ug/ml (lot specific)
Preparation and Storage
Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months.
Avoid repeated freeze/thaw cycles.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customerâs specifications, please inquire.
Other Notes
Small volumes of anti-ACTH antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ACTH antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)
NCBI/Uniprot data below describe general gene information for ACTH. It may not necessarily be applicable to this product.
NCBI Accession #
AAA37169.1
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UniProt Related Accession #
P01193[Other Products]
NCBI Official Full Name
adrenocorticotropic hormone, partial
NCBI Official Synonym Full Names
pro-opiomelanocortin-alpha
NCBI Official Symbol
Pomc [Similar Products]
NCBI Official Synonym Symbols
BE; Npp; ACTH; Clip; Pomc1; Pomc-1; Beta-LPH; alphaMSH; beta-MSH; Gamma-LPH; alpha-MSH; gamma-MSH
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NCBI Protein Information
pro-opiomelanocortin
NCBI Summary for ACTH
This gene encodes a polypeptide hormone precursor that undergoes extensive, tissue-specific, post-translational processing. Processing yields several
biologically active peptides, which are involved in diverse cellular functions, such as energy homeostasis, steroidogenesis, and increased melanin production in melanocytes. In mouse deficiency of this gene is associated with obesity, defects in adrenal development, and altered pigmentation. A pseudogene of this gene is located on chromosome 19. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Research Articles on ACTH
1. After 2 weeks of exposure, CRH and POMC were increased significantly in Sham but not in VL mice. After 8 weeks of exposure, the hypothalamic feeding-related neuropeptides were comparable between Sham and VL mice.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.