Product Name
AGGF1, cDNA Clone
Full Product Name
AGGF1 cDNA Clone
Product Gene Name
AGGF1 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atggcctcgg aggcgccgtc cccgccgcgg tcgccgccgc cgcccacctc ccccgagcct gagctggccc agctaaggcg gaaggtggag aagttggaac gtgaactgcg gagctgcaag cggcaggtgc gggagatcga gaagctgctg catcacacag aacggctgta ccagaacgca gaaagcaaca accaggagct ccgcacgcag gtggaagaac tcagtaaaat actccaacgt gggagaaatg aagataataa aaagtctgat gtagaagtac aaacagagaa ccatgctcct tggtcaatct cagattattt ttatcagacg tactacaatg acgttagtct tccaaataaa gtgactgaac tgtcagatca acaagatcaa gctatcgaaa cttctatttt gaattctaaa gaccatttac aagtagaaaa tgatgcttac cctggtaccg atagaacaga aaatgttaaa tatagacaag tggaccattt tgcctcaaat tcacaggagc cagcatctgc attagcaaca gaagatacct ccttagaagg ctcatcatta gctgaaagtt tgagagctgc agcagaagcg gctgtatcac agactggatt tagttatgat gaaaatactg gactgtattt tgaccacagc actggtttct attatgattc tgaaaatcaa ctctattatg atccttccac tggaatttat tactattgtg atgtggaaag tggtcgttat cagtttcatt ctcgagtaga tttgcaacct tatccgactt ctagcacaaa acaaagtaaa gataaaaaat tgaagaagaa aagaaaagat ccagattctt ctgcaacaaa tgaggaaaag gatttgaact cagaggatca aaaagccttc agtgttgaac atacaagctg caatgaggaa gaaaatttcg caaatatgaa aaagaaggcc aaaataggca ttcatcacaa aaatagtccc cccaaagtca ctgttccaac tagtggaaat actatagagt ctcctcttca tgaaaacatc tctaattcaa catcatttaa agatgagaaa atcatggaga ctgatagtga accagaggaa ggtgaaatta cagactctca gactgaggat agttatgacg aagccattac cagtgaaggc aatgtaactg cagaagatag tgaggatgaa gatgaagaca aaatttggcc cccatgtatt agagtaattg tcattagatc acctgtgttg cagataggat cactctttat cattactgct gtaaaccctg ctacaattgg aagagaaaag gatatggaac atactctccg aatccctgaa gttggtgtca gtaagtttca tgcagaaatt tattttgacc atgacttaca aagttatgtc cttgtggatc aaggcagtca aaatggcaca attgttaatg gaaaacagat tcttcagccg aaaactaaat gtgaccctta cgtacttgag catggagatg aagtcaaaat tggagaaact gtcttatcct ttcacattca tcctggcagt gatacctgtg atggctgtga acgagggcag gttagagccc accttcgcct tgataagaaa gatgaatctt ttgttggtcc aacactaagt aaggaggaaa aagagttgga aggaagaaaa gaattaaaga aaatacgagt aaaatatggt ttacagaata cagaatacga agatgaaaag acattgaaga atccaaaata taaagataga gctggaaaac gtagggagca ggttggaagt gaaggaactt tccaaagaga tgatgctcct gcatctgttc attctgaaat tactgatagc aacaaaggtc ggaagttgtt ggagaagatg ggttggaaga aaggagaggg cctggggaag gatggtggag gaatgaaaac gccgatccag cttcagcttc ggcgaacaca tgcaggcttg gggacaggca aaccatcctc atttgaagat gttcaccttc tccaaaacaa gaacaaaaaa aactgggaca aagcacgaga gcggtttact gaaaacttcc cagaaactaa gcctcaaaaa gatgacccag ggaccatgcc ttgggtaaaa gggactttag agtga
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of AGGF1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for AGGF1. It may not necessarily be applicable to this product.
NCBI Accession #
BC032844
[Other Products]
UniProt Secondary Accession #
O00581; Q53YS3; Q9BU84; Q9NW66[Other Products]
UniProt Related Accession #
Q8N302[Other Products]
Molecular Weight
20,506 Da
NCBI Official Full Name
Homo sapiens angiogenic factor with G patch and FHA domains 1, mRNA
NCBI Official Synonym Full Names
angiogenic factor with G-patch and FHA domains 1
NCBI Official Symbol
AGGF1 [Similar Products]
NCBI Official Synonym Symbols
VG5Q; GPATC7; GPATCH7; HSU84971; HUS84971
[Similar Products]
NCBI Protein Information
angiogenic factor with G patch and FHA domains 1
UniProt Protein Name
Angiogenic factor with G patch and FHA domains 1
UniProt Synonym Protein Names
Angiogenic factor VG5Q; hVG5Q; G patch domain-containing protein 7; Vasculogenesis gene on 5q protein
Protein Family
Angiogenic factor with G patch and FHA domains
UniProt Gene Name
AGGF1 [Similar Products]
UniProt Synonym Gene Names
GPATC7; GPATCH7; VG5Q; hVG5Q [Similar Products]
UniProt Entry Name
AGGF1_HUMAN
NCBI Summary for AGGF1
This gene encodes an angiogenic factor that promotes proliferation of endothelial cells. Mutations in this gene are associated with a susceptibility to Klippel-Trenaunay syndrome. Pseudogenes of this gene are found on chromosomes 3, 4, 10 and 16.[provided by RefSeq, Sep 2010]
UniProt Comments for AGGF1
AGGF1: Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion. Defects in AGGF1 are a cause of Klippel-Trenaunay syndrome (KTS). KTS is a congenital disease characterized by malformations of capillary (98% of KTS patients), venous (72%) and lymphatic (11%) vessels, and bony and soft tissue hypertrophy that leads to large cutaneous hemangiomata with hypertrophy of the related bones and soft tissues. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: RNA processing; Cell adhesion
Chromosomal Location of Human Ortholog: 5q13.3
Cellular Component: cytoplasm; extracellular region; nuclear speck; perinuclear region of cytoplasm
Molecular Function: protein binding; RNA binding
Biological Process: cell adhesion; mRNA processing; positive regulation of angiogenesis; positive regulation of endothelial cell proliferation; regulation of RNA splicing; RNA processing; vasculogenesis
Disease: Klippel-trenaunay-weber Syndrome
Research Articles on AGGF1
1. Overexpression of AGGF1 is correlated with angiogenesis in hepatocellular carcinoma.
Precautions
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Disclaimer
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