Complement 1 Inhibitor (C1INH), Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures.

Chromosome: 2; NC_000068.7 (84765360..84775429, complement). Location: 2 D; 2

E. coli

> 97%

PBS, pH7.4, containing 0.01% SKL.

Original Concentration: 200ug/ml (lot specific)

Storage: Avoid repeated freeze/thaw cycles.
Store at 2-8ºC for one month.
Aliquot and store at -80ºC for 12 months.

Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customer’s specifications, please inquire.

Small volumes of C1INH recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Positive Control; Immunogen; SDS-PAGE; Western Blot (WB)
(May be suitable for use in other assays to be determined by the end user.)

Predicted Molecular Mass: 14.7kDa
Accurate Molecular Mass: 15kDa as determined by SDS-PAGE reducing conditions.

serine (or cysteine) peptidase inhibitor, clade G, member 1

plasma protease C1 inhibitor; C1 Inh; serpin G1; C1-inhibiting factor; C1 esterase inhibitor; complement component 1 inhibitor; serine (or cysteine) proteinase inhibitor, clade G, member 1; serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1

Plasma protease C1 inhibitor

C1nh; C1 Inh; C1Inh  [Similar Products]

IC1_MOUSE

SERPING1: a protein protease inhibitor (C1-inhibitor) that forms a proteolytically inactive stoichiometric complex with the C1r or C1s proteases. May play an important role in regulating complement activation, blood coagulation, fibrinolysis and the generation of kinins. Very efficient inhibitor of FXIIa. Mutations of the SERPING1 gene is associated with ***** macular degeneration can also cause hereditary angioedema. Binds to E.coli stcE which allows localization of SERPING1 to cell membranes thus protecting the bacteria against complement-mediated lysis. Belongs to the serpin family.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular space; extracellular region

Molecular Function: complement binding; serine-type endopeptidase inhibitor activity; protease inhibitor activity

Biological Process: negative regulation of complement activation, lectin pathway; fibrinolysis; immune system process; negative regulation of complement activation; hemostasis; regulation of blood coagulation; negative regulation of peptidase activity; innate immune response; blood coagulation; complement activation, classical pathway

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While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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