Product Name
tryptophan rich basic protein (WRB), ELISA Kit
Full Product Name
Human Tryptophan-rich protein, WRB ELISA Kit
Product Synonym Names
Human Tryptophan-rich protein (WRB) ELISA kit; CHD5; FLJ51808; congenital heart disease 5 protein; tryptophan rich basic protein
Product Gene Name
WRB elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for O00258
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of WRB elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for WRB purchase
MBS9341697 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the tryptophan rich basic protein (WRB) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing WRB. The ELISA analytical biochemical technique of the MBS9341697 kit is based on WRB antibody-WRB antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect WRB antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, WRB. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for WRB. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001139690.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001146218.1
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UniProt Primary Accession #
O00258
[Other Products]
UniProt Secondary Accession #
O60740; A8KAP8; A8MQ44; D3DSH9[Other Products]
UniProt Related Accession #
O00258[Other Products]
Molecular Weight
19,780 Da
NCBI Official Full Name
tail-anchored protein insertion receptor WRB isoform 2
NCBI Official Synonym Full Names
tryptophan rich basic protein
NCBI Official Symbol
WRB [Similar Products]
NCBI Official Synonym Symbols
CHD5
[Similar Products]
NCBI Protein Information
tail-anchored protein insertion receptor WRB; tryptophan-rich protein; tryptophan-rich basic protein; congenital heart disease 5 protein
UniProt Protein Name
Tail-anchored protein insertion receptor WRB
UniProt Synonym Protein Names
Congenital heart disease 5 protein; Tryptophan-rich basic protein; WRB
Protein Family
Tail-anchored protein insertion receptor
UniProt Gene Name
WRB [Similar Products]
UniProt Synonym Gene Names
CHD5; WRB [Similar Products]
UniProt Entry Name
WRB_HUMAN
NCBI Summary for WRB
This gene encodes a basic nuclear protein of unknown function. The gene is widely expressed in ***** and fetal tissues. Since the region proposed to contain the gene(s) for congenital heart disease (CHD) in Down syndrome (DS) patients has been restricted to 21q22.2-22.3, this gene, which maps to 21q22.3, has a potential role in the pathogenesis of Down syndrome congenital heart disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]
UniProt Comments for WRB
WRB: Receptor for ASNA1/TRC40-mediated insertion of tail- anchored (TA) proteins into the ER membrane. Belongs to the WRB/GET1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Chromosomal Location of Human Ortholog: 21q22.3
Cellular Component: endoplasmic reticulum membrane; integral to membrane; nucleus
Research Articles on WRB
1. Results indicate calcium-modulating cyclophilin ligand (CAML) and WRB as components of the TRC40 receptor complex and a crucial mechanism for driving ER membrane insertion of TA proteins in mammalian cells.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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