Product Name
Angiogenic factor with G patch and FHA domains 1 (AGGF1), Recombinant Protein
Full Product Name
Recombinant Human Angiogenic factor with G patch and FHA domains 1 (AGGF1)
Product Gene Name
AGGF1 recombinant protein
[Similar Products]
Product Synonym Gene Name
AGGF1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
2-714aa, Full Length of Mature Protein
Sequence
ASEAPSPPRS PPPPTSPEPE LAQLRRKVEK LERELRSCKR QVREIEKLLH HTERLYQNAE SNNQELRTQV EELSKILQRG RNEDNKKSDV EVQTENHAPW SISDYFYQTY YNDVSLPNKV TELSDQQDQA IETSILNSKD HLQVENDAYP GTDRTENVKY RQVDHFASNS QEPASALATE DTSLEGSSLA ESLRAAAEAA VSQTGFSYDE NTGLYFDHST GFYYDSENQL YYDPSTGIYY YCDVESGRYQ FHSRVDLQPY PTSSTKQSKD KKLKKKRKDP DSSATNEEKD LNSEDQKAFS VEHTSCNEEE NFANMKKKAK IGIHHKNSPP KVTVPTSGNT IESPLHENIS NSTSFKDEKI METDSEPEEG EITDSQTEDS YDEAITSEGN VTAEDSEDED EDKIWPPCIR VIVIRSPVLQ IGSLFIITAV NPATIGREKD MEHTLRIPEV GVSKFHAEIY FDHDLQSYVL VDQGSQNGTI VNGKQILQPK TKCDPYVLEH GDEVKIGETV LSFHIHPGSD TCDGCEPGQV RAHLRLDKKD ESFVGPTLSK EEKELERRKE LKKIRVKYGL QNTEYEDEKT LKNPKYKDRA GKRREQVGSE GTFQRDDAPA SVHSEITDSN KGRKMLEKMG WKKGEGLGKD GGGMKTPIQL QLRRTHAGLG TGKPSSFEDV HLLQNKNKKN WDKARERFTE NFPETKPQKD DPGTMPWVKG TLE
3D Structure
ModBase 3D Structure for Q8N302
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of AGGF1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for AGGF1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_060516.2
[Other Products]
NCBI GenBank Nucleotide #
NM_018046.4
[Other Products]
UniProt Primary Accession #
Q8N302
[Other Products]
UniProt Secondary Accession #
O00581; Q53YS3; Q9BU84; Q9NW66[Other Products]
UniProt Related Accession #
Q8N302[Other Products]
Molecular Weight
20,506 Da
NCBI Official Full Name
angiogenic factor with G patch and FHA domains 1
NCBI Official Synonym Full Names
angiogenic factor with G-patch and FHA domains 1
NCBI Official Symbol
AGGF1 [Similar Products]
NCBI Official Synonym Symbols
VG5Q; GPATC7; GPATCH7; HSU84971; HUS84971
[Similar Products]
NCBI Protein Information
angiogenic factor with G patch and FHA domains 1
UniProt Protein Name
Angiogenic factor with G patch and FHA domains 1
UniProt Synonym Protein Names
Angiogenic factor VG5Q; hVG5Q; G patch domain-containing protein 7; Vasculogenesis gene on 5q protein
Protein Family
Angiogenic factor with G patch and FHA domains
UniProt Gene Name
AGGF1 [Similar Products]
UniProt Synonym Gene Names
GPATC7; GPATCH7; VG5Q; hVG5Q [Similar Products]
NCBI Summary for AGGF1
This gene encodes an angiogenic factor that promotes proliferation of endothelial cells. Mutations in this gene are associated with a susceptibility to Klippel-Trenaunay syndrome. Pseudogenes of this gene are found on chromosomes 3, 4, 10 and 16.[provided by RefSeq, Sep 2010]
UniProt Comments for AGGF1
Promotes angiogenesis and the proliferation of endothelial cells. Able to bind to endothelial cells and promote cell proliferation, suggesting that it may act in an autocrine fashion.
Research Articles on AGGF1
1. Aggf1 has a role in regulating vascular injury.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
