glucose 6 phosphatase, catalytic, 3, ELISA Kit

Mouse Glucose-6-phosphatase 3 (G6PC3) ELISA kit; SCN4; UGRP; G6Pase-beta; glucose-6-phosphatase catalytic subunit 3; ubiquitously expressed G6Pase catalytic subunit-related protein; glucose 6 phosphatase; catalytic; 3

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of G6PC3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9336648 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the glucose 6 phosphatase, catalytic, 3 (G6PC3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing G6PC3. The ELISA analytical biochemical technique of the MBS9336648 kit is based on G6PC3 antibody-G6PC3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect G6PC3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, G6PC3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

38,782 Da

glucose 6 phosphatase, catalytic, 3

glucose-6-phosphatase 3; G6Pase 3; G-6-Pase 3; glucose-6-phosphatase catalytic subunit-related; ubiquitous glucose-6-phosphatase catalytic subunit-related protein

Glucose-6-phosphatase 3

Ugrp; G-6-Pase 3; G6Pase 3  [Similar Products]

G6PC3_MOUSE

G6PC3: Hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum. May form with the glucose-6-phosphate transporter (SLC37A4/G6PT) a ubiquitously expressed complex responsible for glucose production through glycogenolysis and gluconeogenesis. Probably required for normal neutrophil function. Defects in G6PC3 are the cause of neutropenia severe congenital autosomal recessive type 4 (SCN4). Autosomal recessive SCN constitutes a primary immunodeficiency syndrome associated with increased apoptosis in myeloid cells. Individuals show a paucity of mature neutrophils in peripheral blood and bone marrow and develop life-threatening bacterial infections. SCN4 is a severe congenital neutropenia syndrome associated with cardiac and urogenital malformations. Defects in G6PC3 are the cause of Dursun syndrome (DURSS). A disease characterized by pulmonary arterial hypertension, cardiac abnormalities including secundum-type atrial septal defect, intermittent neutropenia, lymphopenia, monocytosis and anemia. Belongs to the glucose-6-phosphatase family.

Protein type: Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral; Phosphatase (non-protein); Transporter; EC 3.1.3.9

Cellular Component: membrane; endoplasmic reticulum; integral to membrane; integral to endoplasmic reticulum membrane

Molecular Function: hydrolase activity; glucose-6-phosphatase activity; catalytic activity

Biological Process: dephosphorylation; glucose-6-phosphate transport; glucose 6-phosphate metabolic process; phosphate metabolic process; gluconeogenesis

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