Product Name
SLC2A9, siRNA
Full Product Name
SLC2A9 siRNA (Human)
Product Synonym Names
GLUT9; Solute carrier family 2. facilitated glucose transporter member 9; Glucose transporter type 9; GLUT-9
Product Gene Name
SLC2A9 sirna
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9NRM0
Specificity
SLC2A9 siRNA (Human) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
Purity/Purification
> 97%
Form/Format
Lyophilized powder
Quality Control
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Directions for Use
We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
Components
We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of human SLC2A9 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Negative Control
siRNA Negative Control (Catalog# MBS8241404) is a non-targeting 21 nt siRNA recommended as a negative control for experiments using targeted siRNA transfection.
Other Notes
Small volumes of SLC2A9 sirna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
SLC2A9 sirna
siRNA to inhibit SLC2A9 expression using RNA interference
Applications Tested/Suitable for SLC2A9 sirna
RNA Interference (RNAi)
NCBI/Uniprot data below describe general gene information for SLC2A9. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001001290.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001001290.1
[Other Products]
UniProt Primary Accession #
Q9NRM0
[Other Products]
UniProt Secondary Accession #
Q0VGC4; Q4W5D1; Q8WV30; Q96P00[Other Products]
UniProt Related Accession #
Q9NRM0[Other Products]
Molecular Weight
55,721 Da
NCBI Official Full Name
solute carrier family 2, facilitated glucose transporter member 9 isoform 2
NCBI Official Synonym Full Names
solute carrier family 2 (facilitated glucose transporter), member 9
NCBI Official Symbol
SLC2A9 [Similar Products]
NCBI Official Synonym Symbols
GLUT9; GLUTX; UAQTL2; URATv1
[Similar Products]
NCBI Protein Information
solute carrier family 2, facilitated glucose transporter member 9
UniProt Protein Name
Solute carrier family 2, facilitated glucose transporter member 9
UniProt Synonym Protein Names
Glucose transporter type 9; GLUT-9
Protein Family
Solute carrier family
UniProt Gene Name
SLC2A9 [Similar Products]
UniProt Synonym Gene Names
GLUT9; GLUT-9 [Similar Products]
UniProt Entry Name
GTR9_HUMAN
NCBI Summary for SLC2A9
This gene encodes a member of the SLC2A facilitative glucose transporter family. Members of this family play a significant role in maintaining glucose homeostasis. The encoded protein may play a role in the development and survival of chondrocytes in cartilage matrices. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for SLC2A9
GLUT9: an integral membrane facilitative glucose transporter. One of 13 members of the human equilibrative glucose transport protein family.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter; Transporter, SLC family
Chromosomal Location of Human Ortholog: 4p16.1
Cellular Component: integral to plasma membrane; basolateral plasma membrane; apical plasma membrane; plasma membrane; integral to membrane; nuclear envelope
Molecular Function: sugar:hydrogen ion symporter activity; glucose transmembrane transporter activity
Biological Process: proton transport; urate metabolic process; glucose transport; transmembrane transport
Disease: Hypouricemia, Renal, 2
Research Articles on SLC2A9
1. Single-nucleotide polymorphisms (SNP) rs2231137(C9T) and rs2231142 (C9A) of ABCG2 were found in this familial aggregation of Chinese female premenopausal gout.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
