CLEC12A, Polyclonal Antibody

CLL1; MICL; CD371; CLL-1; DCAL-2

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

The antibody detects endogenous levels of total CLEC12A protein.

Antigen affinity purification

In pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

0.5mg/ml (lot specific)

Store at -20 degree C.

Small volumes of anti-CLEC12A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13.

Total protein Ab

Immunohistochemistry (IHC)

IF: 1: 20-100

The image is immunohistochemistry of paraffin-embedded Human brain tissue using 46945(CCP110 Antibody) at dilution 1/20. (Original magnification: 200)

24,449 Da

C-type lectin domain family 12 member A

C-type lectin domain family 12 member A

C-type lectin domain family 12 member A

CLL1; DCAL2; MICL; CLL-1; DCAL-2; MICL  [Similar Products]

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13. [provided by RefSeq, May 2011]

Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.

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