Full Product Name
GPR17 Antibody
Product Synonym Names
Uracil nucleotide/cysteinyl leukotriene receptor; UDP/CysLT receptor; G-protein coupled receptor 17; P2Y-like receptor; R12; GPR17
Product Gene Name
anti-GPR17 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence Positions
171-230
3D Structure
ModBase 3D Structure for Q13304
Species Reactivity
Human, mouse, rat
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
0.01M PBS, pH 7.2, 0.1% Sodium azide, Glycerol 50%
Concentration
1mg/ml (lot specific)
Antigen Type
synthetic peptide
Antigen Source
KLH conjugated synthetic peptide derived from human GPR17
Preparation and Storage
Store at -20 degree C.Stable for 12 months from date of receipt
Other Notes
Small volumes of anti-GPR17 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GPR17 antibody
Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.
Product Categories/Family for anti-GPR17 antibody
Neuroscience; Signal Transduction
Applications Tested/Suitable for anti-GPR17 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-GPR17 antibody
WB~~ 1:1000
Western Blot (WB) of anti-GPR17 antibody
Anti-GPR17 Antibodyat 1:1000 dilution + human kidney lysates
Lysates/proteins at 20 ug per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution
Predicted band size : 41 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
NCBI/Uniprot data below describe general gene information for GPR17. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001154887.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001161415.1
[Other Products]
UniProt Primary Accession #
Q13304
[Other Products]
UniProt Secondary Accession #
Q8N5S7; Q9UDZ6; Q9UE21; A8K9L0; B2R9X0[Other Products]
UniProt Related Accession #
Q13304[Other Products]
NCBI Official Full Name
uracil nucleotide/cysteinyl leukotriene receptor isoform a
NCBI Official Synonym Full Names
G protein-coupled receptor 17
NCBI Official Symbol
GPR17 [Similar Products]
NCBI Protein Information
uracil nucleotide/cysteinyl leukotriene receptor
UniProt Protein Name
Uracil nucleotide/cysteinyl leukotriene receptor
UniProt Synonym Protein Names
G-protein coupled receptor 17; P2Y-like receptor; R12
Protein Family
Uracil nucleotide/cysteinyl leukotriene receptor
UniProt Gene Name
GPR17 [Similar Products]
UniProt Synonym Gene Names
UDP/CysLT receptor [Similar Products]
UniProt Entry Name
GPR17_HUMAN
UniProt Comments for GPR17
GPR17: Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integral
Chromosomal Location of Human Ortholog: 2q21
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: chemokine receptor activity
Biological Process: G-protein coupled receptor protein signaling pathway
Product References and Citations for anti-GPR17 antibody
Raport C.J.,et al.J. Leukoc. Biol. 59:18-23(1996).
Blaesius R.H.,et al.J. Neurochem. 70:1357-1365(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Ciana P.,et al.EMBO J. 25:4615-4627(2006).
Research Articles on GPR17
1. GPR17 gene disruption does not alter food intake or glucose homeostasis in mice.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
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