Product Name
ZNF750, cDNA Clone
Full Product Name
ZNF750 cDNA Clone
Product Gene Name
ZNF750 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
ATGAGTCTCC TCAAAGAGCG GAAGCCAAAA AAGCCACATT ACATCCCCAG GCCTCCAGGA AAGCCCTTCA AGTATAAATG TTTCCAATGT CCCTTTACTT GCAATGAGAA GTCACATCTT TTTAATCACA TGAAGTATGG TCTTTGTAAA AACTCGATTA CTTTAGTATC AGAGCAGGAT CGAGTTCCCA AGTGCCCTAA ATCTAACTCA CTAGACCCCA AGCAAACCAA CCAGCCCGAT GCCACGGCGA AGCCAGCCTC TTCCAAGTCT GTCGCAAATG GACTCTCTGC CTTCGACTCG AAGCTTCAGC ACAGCTCTGC CAGGGAAGAC ATCAAGGAAA ACCTGGAGCT GCAAGCCCGG GGAACCCACA GGTGCCTGGG ACAGAAGCCA GCCCTCCACA GGGCATCACC CTGCAAGAGC CCAGCTCCGG AAGCCGCCCT CGGTGCCCAG CCTGCTCTGG AAGGCGCAGC TCGGCCTTCT GCATTTGTTC CAGTCGGCGA GCACAGACTC AAGGGGCCAG ACAACGCCGA GGCGCCCGAG ACACTGGCTT TACACAACCC CACTGCCAAG GCCGTGTCTT TCCACACCAA GTCGGCCTTC CACACTCCTG GCTACCCCTG GAAAGCCGGC TCACCTTTCC TTCCACCAGA GTTTCCACAT AAAATCTCAT CTACAAAGGG GCTTGGGGCC ATTTCCCCTT ACATGCACCC CACAATCCCA GAGTACCCGC CTCACTTTTA CACAGAGCAC GGGCTGGCCA CCATCTACTC GCCTTACCTG CTGGCTGGGA GCTCGCCTGA GTGTGACGCA CCCCTGCTGT CAGTCTACGG AACCCAAGAC CCGAGACACT TCCTGCCTCA CCCGGGGCCG ATCCCTAAGC ACCTGGCTCC ATCTCCAGCC ACATACGATC ACTACAGGTT TTTCCAGCAA TATCCCTCTA ACCTGCCGAT TCCTTACGGA TTTTACAGGC CAGAGTCTGC ATTTTCCTCC TATGGTCTCA GACTCCCACC TGTCACTGGC CTCACCCGAG ATCAGAGCTC TCACCTGCTT GAAGAAGCCA CCCTGGTCTA TCCAGCCTCG AGTCCTTCCA GGTTAAACCC TTCGGACCCC AACAGAAAAC ACGTCGAGTT CGAAAGTCCA ATTCCTGAGG CTAAAGACTC CTCCAAGGCT GGGCAGAGAG ACACGGAAGG GTCCAAAATG AGCCCCCGCG CAGGGAGTGC AGCCACGGGC TCCCCAGGGA GGCCGAGCCC CACCGACTTC ATGCAGACGA GCCAGACCTG CGAAGGCCTG TACGACCTCT CCAACAAGGC AGCCTCCAGC GCACTGGGAA GACTCTACCC GCCAGAGCAA AGCCTCACAG CCTTCAGGCC TGTTAAGAAA AGCACAGAAT GCCTACCTGC CCAGGCTGCT GAGACCACAG CAGAGTCTCC AGTAAGCCTC AATGTTGTGA ACGGAGACCC TCCTGCTCCG ACCGGAAGCG CCTCTCTCGT CTCGGAGGCC GCGCCTTCCA GTCCGGACGA CAGCTCCGGG ATGGGCCCCC TCAACCTCTC CAAGAAATCA GAGATAAACC TGGCAGCCAC CCACGAACCC ACGTACCAAG GCAGCCCCCA GGCGGAAACC GCCAGCTTCT CAGAGCTGCA GGACCTTCCA CTCAATCTCT CGGTGAAGGA CCCCTGTAAC ACCCAGGCTC CGAGGCCCGC CTTCCCCGGT CGACCACGAG CTGCGGAACC TGCTGCTGCT GTTCCACAGA AGACTGGGAC AGAAGGTTCT GAGGATGGGC CCAGCCACCC TGAGACCAAG CCAGGCAGCC TCGACGGTGA CGGGGCCCCA CCCACAGGCC CCGGCGAGGA GGCTCCAGAC GCATGCGCGG TGGACAGCAG CGAGGAGCAG AAGCAGACGG CAGCCGTGGC CCTGTGCCAG CTGGCGGCCT ACAGCCCCAG GAACATCCGG GTGGGCGATG GGGATGCTGC GGCCCCGGAA CCTGCCTGCC GGCAAGACAC ACCCACACTG AGCTCCATGG AGAGCCAAGA GGCCCAGTGT GACCTCAGAC CCAAAGGACA AAAGAGGACA AGTCTAAGGG ATGCTGGAAA ATCCCAGCAA GGAGCTAAGA AGGCGAAGCT GCAGGACACG GCCAGAGTGT TCACACTACG AAGGAGGGCC CGGGTGTCCT AA
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ZNF750 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ZNF750. It may not necessarily be applicable to this product.
NCBI Accession #
BC109037
[Other Products]
UniProt Secondary Accession #
Q9H899[Other Products]
UniProt Related Accession #
Q32MQ0[Other Products]
Molecular Weight
77,361 Da
NCBI Official Full Name
Homo sapiens zinc finger protein 750, mRNA
NCBI Official Synonym Full Names
zinc finger protein 750
NCBI Official Symbol
ZNF750 [Similar Products]
NCBI Official Synonym Symbols
ZFP750
[Similar Products]
NCBI Protein Information
zinc finger protein 750
UniProt Protein Name
Zinc finger protein 750
Protein Family
Zinc finger protein
UniProt Gene Name
ZNF750 [Similar Products]
UniProt Entry Name
ZN750_HUMAN
NCBI Summary for ZNF750
This gene encodes a protein with a nuclear localization site and a C2H2 zinc finger domain. Mutations in this gene have been associated with seborrhea-like dermatitis with psoriasiform elements. [provided by RefSeq, Jul 2008]
UniProt Comments for ZNF750
ZNF750: Transcription factor involved in epidermis differentiation. Required for terminal epidermal differentiation: acts downstream of p63/TP63 and activates expression of late epidermal differentiation genes. Specifically binds to the promoter of KLF4 and promotes its expression. Defects in ZNF750 are the cause of Seborrhea-like dermatitis with psoriasiform (SLDP). SLDP is characterized by a chronic fine diffuse scaly erythematous rash on the face, particularly on the chin, nasolabial folds and eyebrows, around earlobes and over the scalp. The rash exacerbate in the winter, with emotional stress and after strenuous physical activity. Hyperkeratosis of skin over the elbows, knees, palms, soles and metacarpophalangeal joints is evident. There is no arthralgia, arthritis or neurological disorders.
Protein type: C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 17q25.3
Cellular Component: intracellular membrane-bound organelle; nucleolus; nucleus
Molecular Function: protein binding
Biological Process: epidermis development; positive regulation of transcription from RNA polymerase II promoter
Disease: Seborrhea-like Dermatitis With Psoriasiform Elements
Research Articles on ZNF750
1. Suggest no connection of ZNF750 variants with psoriasis or its subphenotypes.
Precautions
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Disclaimer
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