Full Product Name
Bovine UCN3 Polyclonal Antibody
Product Synonym Names
SPC; Urocortin III; Ucn III
Product Gene Name
anti-UCN3 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q969E3
Purity/Purification
Immunogen Affinity Purified
Form/Format
Liquid; 0.1MxPBS, 50% Glycerol, pH7.5
Concentration
200 ug/ml (lot specific)
Immunogen
Recombinant Human UCN3 Protein
Preparation and Storage
Store at 4 degree C for frequent use. Store at -20 degree C to -70 degree C for 6 months.
Other Notes
Small volumes of anti-UCN3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-UCN3 antibody
Western Blot (WB), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for UCN3. It may not necessarily be applicable to this product.
NCBI GenBank Nucleotide #
NP_444277.2
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UniProt Primary Accession #
Q969E3
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UniProt Related Accession #
Q969E3[Other Products]
NCBI Official Full Name
urocortin-3 preproprotein
NCBI Official Synonym Full Names
urocortin 3
NCBI Official Symbol
UCN3 [Similar Products]
NCBI Official Synonym Symbols
SCP; SPC; UCNIII
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NCBI Protein Information
urocortin-3
UniProt Protein Name
Urocortin-3
UniProt Synonym Protein Names
Stresscopin; Urocortin III; Ucn III
UniProt Gene Name
UCN3 [Similar Products]
UniProt Synonym Gene Names
SPC; Ucn III [Similar Products]
NCBI Summary for UCN3
This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family of proteins. The encoded preproprotein is proteolytically processed to generate the mature peptide hormone, which is secreted by pancreatic beta and alpha cells. This hormone is an endogenous ligand for corticotropin-releasing factor receptor 2 and may regulate insulin secretion in response to plasma glucose levels. Patients with type 2 diabetes exhibit reduced levels of the encoded protein in beta cells. In the brain, the encoded protein may be responsible for the effects of stress on appetite. [provided by RefSeq, May 2016]
UniProt Comments for UCN3
Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress.
Research Articles on UCN3
1. examination of the local and systemic cardiovascular effects of urocortin 2 and urocortin 3 in healthy subjects and patients with heart failure
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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