4-1BB-R, ELISA Kit

Tumor necrosis factor receptor superfamily member 9; 4-1BB ligand receptor T-cell; antigen 4-1BB homolog; T-cell antigen ILA; CD137 antigen; CDw137; ILA; 4-1BB; MGC2172; 4-1BBR; TNFRSF9

For Research Use Only. Not for use in diagnostic procedures.

The OmniKine Human 4-1BBR ELISA is capable of recognizing both recombinant and naturally produced Human 4-1BBR proteins. The antigens listed below were tested at 50 ng/ml and did not exhibit significant cross reactivity or interference.
Human: 4-1BBL, AITRL, BAFF, BAFF Receptor, BCMA, CD40 Ligand/TRAP, Fas Receptor, LIGHT, OPG, sOX40L, sRANK (Receptor), sRANKL, TACI, TL-1A, TNF-alpha, TNF-beta, sTNF-Receptor Type I, sTNF-Receptor Type II, sTRAIL/Apo2L, sTRAIL Receptor-1, sTRAIL Receptor-2, TWEAK, TWEAK Receptor

12 x 8-Well Microstrips

Store at 4 degree C for 6 months.

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of 4-1BB-R elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9501827 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the 4-1BB-R, ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing 4-1BB-R. The ELISA analytical biochemical technique of the MBS9501827 kit is based on 4-1BB-R antibody-4-1BB-R antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect 4-1BB-R antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, 4-1BB-R. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

The OmniKine Human 4-1BB-R ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human 4-1BB-R proteins within the range of 16-2000 pg/ml.

27,899 Da

TNF receptor superfamily member 9

tumor necrosis factor receptor superfamily member 9

Tumor necrosis factor receptor superfamily member 9

CD137; ILA  [Similar Products]

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]

TNFRSF9: Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 1p36.23

Cellular Component: external side of plasma membrane; extracellular space; integral component of plasma membrane; plasma membrane

Molecular Function: cytokine binding; receptor activity; tumor necrosis factor-activated receptor activity

Biological Process: apoptosis; immune response; inflammatory response; multicellular organism development; negative regulation of cell proliferation; regulation of apoptosis; regulation of cell proliferation; response to lipopolysaccharide; tumor necrosis factor-mediated signaling pathway

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.