Full Product Name
EVL Antibody
Product Synonym Names
RNB6
Product Gene Name
anti-EVL antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Immunogen
Fusion protein of EVL
Calculated Molecular Weight: 418aa; 45kd
Observed Molecular Weight: 50kd
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-66527 / sc-66527 / sc-25532 / sc-68405 / sc-68405
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-EVL antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-EVL antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-EVL antibody
WB: 1:500-1:5000
Testing Data of anti-EVL antibody
NCBI/Uniprot data below describe general gene information for EVL. It may not necessarily be applicable to this product.
NCBI Accession #
NP_057421.1
[Other Products]
NCBI GenBank Nucleotide #
NM_016337.2
[Other Products]
UniProt Secondary Accession #
O95884; Q7Z522; Q8TBV1; Q9UF25; Q9UIC2; A8K105; B7Z3I5[Other Products]
UniProt Related Accession #
Q9UI08[Other Products]
Molecular Weight
41,577 Da
NCBI Official Full Name
ena/VASP-like protein
NCBI Official Synonym Full Names
Enah/Vasp-like
NCBI Official Symbol
EVL [Similar Products]
NCBI Official Synonym Symbols
RNB6
[Similar Products]
NCBI Protein Information
ena/VASP-like protein; ena/vasodilator-stimulated phosphoprotein-like
UniProt Protein Name
Ena/VASP-like protein
UniProt Synonym Protein Names
Ena/vasodilator-stimulated phosphoprotein-like
Protein Family
Ena/VASP-like protein
UniProt Gene Name
EVL [Similar Products]
UniProt Synonym Gene Names
RNB6 [Similar Products]
UniProt Entry Name
EVL_HUMAN
UniProt Comments for EVL
EVL: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance and lamellipodial and filopodial dynamics in migrating cells. EVL enhances actin nucleation and polymerization. Required to transform actin polymerization into active movement for the propulsive force of Listeria monocytogenes. Belongs to the Ena/VASP family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cytoskeletal; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 14q32.2
Cellular Component: cytoskeleton; focal adhesion; membrane; lamellipodium; cytoplasm; cytosol
Molecular Function: protein binding; actin binding; SH3 domain binding; profilin binding
Biological Process: axon guidance; nervous system development; organ morphogenesis; cell surface receptor linked signal transduction; positive regulation of actin filament polymerization; actin polymerization and/or depolymerization; positive regulation of stress fiber formation; actin filament organization; protein homotetramerization
Research Articles on EVL
1. ENA/VASP-family proteins are functionally redundant in homologous recombination, and MENA, VASP and EVL may be involved in the DSB repair pathway in humans
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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