Product Name
Caspase-12 (Casp12), ELISA Kit
Full Product Name
Rat Caspase-12 ELISA Kit
Product Synonym Names
Caspase-12; CASP-12; Casp12
Product Gene Name
Casp12 elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for Q920D5
Detection Range
0.156-10 ng/mL
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of Casp12 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for Casp12 purchase
MBS2886920 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Caspase-12 (Casp12) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Casp12. The ELISA analytical biochemical technique of the MBS2886920 kit is based on Casp12 antibody-Casp12 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Casp12 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Casp12. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
Typical Testing Data/Standard Curve (for reference only) of Casp12 elisa kit
NCBI/Uniprot data below describe general gene information for Casp12. It may not necessarily be applicable to this product.
NCBI Accession #
NP_569106.1
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NCBI GenBank Nucleotide #
NM_130422.1
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UniProt Primary Accession #
Q920D5
[Other Products]
UniProt Related Accession #
Q920D5[Other Products]
Molecular Weight
47,837 Da
NCBI Official Full Name
caspase-12
NCBI Official Synonym Full Names
caspase 12
NCBI Official Symbol
Casp12 [Similar Products]
NCBI Protein Information
caspase-12
UniProt Protein Name
Caspase-12
UniProt Gene Name
Casp12 [Similar Products]
UniProt Synonym Gene Names
CASP-12 [Similar Products]
UniProt Entry Name
CASPC_RAT
NCBI Summary for Casp12
cysteine-aspartic acid protease (caspase); involved with the terminal stage of apoptosis [RGD, Feb 2006]
UniProt Comments for Casp12
CASP12: Has no protease activity. May reduce cytokine release in response to bacterial lipopolysaccharide during infections. Reduces activation of NF-kappa-B in response to TNF. Detected in heart, kidney, liver, lung, pancreas, small intestine, spleen, stomach, thymus and testis. Belongs to the peptidase C14A family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.4.22.-; Protease
Cellular Component: cytosol; endoplasmic reticulum; intracellular membrane-bound organelle; nucleus
Molecular Function: cysteine-type endopeptidase activity; cysteine-type peptidase activity; endopeptidase activity; protease binding; protein binding
Biological Process: aging; apoptosis; positive regulation of apoptosis; positive regulation of caspase activity; protein autoprocessing; proteolysis; regulation of apoptosis; regulation of inflammatory response; response to anoxia; response to cold; response to drug; response to ethanol; response to inorganic substance; response to iron(III) ion; response to nicotine; response to organic nitrogen; unfolded protein response
Research Articles on Casp12
1. SMI could alleviate myocardial ER stress and caspase-12 dependent apoptosis, which subsequently helped to improve the heart function of rats with DOX-CM.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
