Product Name
ADH1B, Blocking Peptide
Full Product Name
ADH1B Peptide - N-terminal region
Product Gene Name
ADH1B blocking peptide
[Similar Products]
Product Synonym Gene Name
ADH2; DKFZp686C06125[Similar Products]
ADH1B peptide (MBS3230998) is used for blocking the activity of ADH1B antibody (MBS3206035)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P00325
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Other Notes
Small volumes of ADH1B blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ADH1B blocking peptide
This is a synthetic peptide designed for use in combination with anti-ADH1B antibody made
Target Description: ADH1B is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Product Categories/Family for ADH1B blocking peptide
Peptide
Applications Tested/Suitable for ADH1B blocking peptide
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for ADH1B. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000659
[Other Products]
NCBI GenBank Nucleotide #
NM_000668
[Other Products]
UniProt Primary Accession #
P00325
[Other Products]
UniProt Related Accession #
P00325[Other Products]
NCBI Official Full Name
alcohol dehydrogenase 1B isoform 1
NCBI Official Synonym Full Names
alcohol dehydrogenase 1B (class I), beta polypeptide
NCBI Official Symbol
ADH1B [Similar Products]
NCBI Official Synonym Symbols
ADH2; HEL-S-117
[Similar Products]
NCBI Protein Information
alcohol dehydrogenase 1B
UniProt Protein Name
Alcohol dehydrogenase 1B
UniProt Synonym Protein Names
Alcohol dehydrogenase subunit beta
UniProt Gene Name
ADH1B [Similar Products]
UniProt Synonym Gene Names
ADH2 [Similar Products]
UniProt Entry Name
ADH1B_HUMAN
NCBI Summary for ADH1B
The protein encoded by this gene is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This encoded protein, consisting of several homo- and heterodimers of alpha, beta, and gamma subunits, exhibits high activity for ethanol oxidation and plays a major role in ethanol catabolism. Three genes encoding alpha, beta and gamma subunits are tandemly organized in a genomic segment as a gene cluster. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
UniProt Comments for ADH1B
ADH1B: Dimer of identical or non-identical chains of three types; alpha, beta and gamma. Belongs to the zinc-containing alcohol dehydrogenase family.
Protein type: Lipid Metabolism - fatty acid; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Xenobiotic Metabolism - metabolism by cytochrome P450; EC 1.1.1.1; Oxidoreductase; Amino Acid Metabolism - tyrosine; Cofactor and Vitamin Metabolism - retinol; Xenobiotic Metabolism - drug metabolism - cytochrome P450
Chromosomal Location of Human Ortholog: 4q23
Cellular Component: cytosol
Molecular Function: zinc ion binding; alcohol dehydrogenase activity, zinc-dependent
Biological Process: xenobiotic metabolic process; ethanol oxidation
Disease: Alcohol Dependence
Research Articles on ADH1B
1. No evidence of a significant association of ADH1B polymorphism (rs1229984) with gastric cancer was observed.
Precautions
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Disclaimer
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