Full Product Name
CD25 antibody
Product Synonym Names
Monoclonal CD25; Anti-CD25; CD25 IL2-R alpha TACIL2-R alpha TAC; CD 25; CD-25; IL2Ra; CD25
Product Gene Name
anti-CD25 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P25094
Purity/Purification
> 95% pure
CD25 antibody was purified by Protein A chromatography.
Form/Format
50mM Na3PO4, pH 7.5, with 100mM KCL, 150mM NaCl, and 0.5 mg/ml gentamycin sulfate.
Concentration
1.0 mg/ml (lot specific)
Biological Significance
Expression of human CD25 (the alpha subunit of the IL-2 receptor complex) is dramatically upregulated on activated T cells, B cells, NK cells and macrophages. Antibodies to CD25 are being studied for potential use as an immundirected therapy to selectively attack (kill) CD25 expressing cells.
Immunogen
CD25 antibody was raised in mouse using Stimulated PBMC as the immunogen.
Preparation and Storage
Store at 4 degree C.
Other Notes
Small volumes of anti-CD25 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CD25 antibody
Mouse monoclonal CD25 antibody
Product Categories/Family for anti-CD25 antibody
Immunology
Applications Tested/Suitable for anti-CD25 antibody
Flow Cytometry (FC/FACS), Immunohistochemistry (IHC)
Application Notes for anti-CD25 antibody
FC: 5 ug/ml
NCBI/Uniprot data below describe general gene information for CD25. It may not necessarily be applicable to this product.
NCBI Accession #
CAA44297.1
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UniProt Primary Accession #
P25094
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Molecular Weight
17,946 Da
NCBI Official Full Name
CD25
UniProt Protein Name
Peripheral myelin protein 22
UniProt Synonym Protein Names
Protein CD25; SR13 myelin protein; Schwann cell membrane glycoprotein; SAG
UniProt Gene Name
Pmp22 [Similar Products]
UniProt Synonym Gene Names
Cd25; Pmp-22; PMP-22; SAG [Similar Products]
UniProt Entry Name
PMP22_RAT
UniProt Comments for CD25
Might be involved in growth regulation, and in myelinization in the peripheral nervous system.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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