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elaC homolog 2 (E. coli), ELISA Kit

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产品名称: elaC homolog 2 (E. coli), ELISA Kit
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简单介绍

elaC homolog 2 (E. coli), ELISA Kit


elaC homolog 2 (E. coli), ELISA Kit  的详细介绍
Product Name

elaC homolog 2 (E. coli) (ELAC2), ELISA Kit

Full Product Name

Human Zinc phosphodiesterase ELAC protein 2, ELAC2 ELISA Kit

Product Synonym Names
Human Zinc phosphodiesterase ELAC protein 2 (ELAC2) ELISA kit; ELC2; FLJ10530; FLJ36693; FLJ42848; HPC2; elaC homolog 2; putative prostate cancer susceptibility protein HPC2/ELAC2; ribonuclease Z 2; tRNA 3 endonuclease 2; tRNase Z (long form) ; tRNase Z 2; zinc phosph; elaC homolog 2 (E. coli)
Product Gene Name

ELAC2 elisa kit

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Request for Current Manual Insert
Request Current Manual
OMIM
615440
3D Structure
ModBase 3D Structure for Q9BQ52
Species Reactivity
Human
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of ELAC2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for ELAC2 purchase
MBS9341748 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the elaC homolog 2 (E. coli) (ELAC2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ELAC2. The ELISA analytical biochemical technique of the MBS9341748 kit is based on ELAC2 antibody-ELAC2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ELAC2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ELAC2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
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NCBI/Uniprot data below describe general gene information for ELAC2. It may not necessarily be applicable to this product.
NCBI GI #
260166619
NCBI GeneID
60528
NCBI Accession #
NP_001159434.1 [Other Products]
NCBI GenBank Nucleotide #
NM_001165962.1 [Other Products]
UniProt Primary Accession #
Q9BQ52 [Other Products]
UniProt Secondary Accession #
Q6IA94; Q9HAS8; Q9HAS9; Q9NVT1; B4DPL9[Other Products]
UniProt Related Accession #
Q9BQ52[Other Products]
Molecular Weight
92,219 Da
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NCBI Official Full Name
zinc phosphodiesterase ELAC protein 2 isoform 3
NCBI Official Synonym Full Names
elaC ribonuclease Z 2
NCBI Official Symbol
ELAC2  [Similar Products]
NCBI Official Synonym Symbols
ELC2; HPC2; COXPD17
  [Similar Products]
NCBI Protein Information
zinc phosphodiesterase ELAC protein 2; RNase Z 2; tRNase Z 2; elaC homolog 2; ribonuclease Z 2; tRNase Z (long form); tRNA 3 endonuclease 2; elaC homolog protein 2; heredity prostate cancer protein 2; putative prostate cancer susceptibility protein HPC2/ELAC2
UniProt Protein Name
Zinc phosphodiesterase ELAC protein 2
UniProt Synonym Protein Names
ElaC homolog protein 2; Heredity prostate cancer protein 2; Ribonuclease Z 2; RNase Z 2; tRNA 3 endonuclease 2; tRNase Z 2
Protein Family
Zinc phosphodiesterase ELAC protein
UniProt Gene Name
ELAC2  [Similar Products]
UniProt Synonym Gene Names
HPC2; RNase Z 2  [Similar Products]
UniProt Entry Name
RNZ2_HUMAN
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NCBI Summary for ELAC2
The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
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UniProt Comments for ELAC2
ELAC2: a zinc phosphodiesterase. Putative prostate cancer susceptibility protein.

Protein type: EC 3.1.26.11; Ribonuclease; RNA processing; Oncoprotein; Phosphodiesterase

Chromosomal Location of Human Ortholog: 17p11.2

Cellular Component: nucleoplasm; mitochondrion; nucleus

Molecular Function: endonuclease activity; metal ion binding

Disease: Prostate Cancer, Hereditary, 2; Combined Oxidative Phosphorylation Deficiency 17
Research Articles on ELAC2
1. ELAC2 mutations cause a mitochondrial RNA processing defect associated with hypertrophic cardiomyopathy.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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