Product Name
Presenilins-associated rhomboid-like protein (parl), Recombinant Protein
Full Product Name
Recombinant Danio rerio Presenilins-associated rhomboid-like protein, mitochondrial (parl)
Product Gene Name
parl recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
38-383aa; full length protein
Sequence
FRKTERPSES KKGVQETEAE AGGHNRAVPP KPVPPLPPRR PHQLFRPLVF TVGFTGCSFG AAAILQYESV KSRVQLAIEE AKEEKRDTLL EGHDTTYWHN WWNQLSNFQK QVILLISAVD DFWSGLSEGQ KTVTGIIALN TVVLCCWRVP AMQRFLVKYF TSNPASKTRC LPMVLSSFSH YSVIHMVVNM YVLWTFSSSI VSLLGREQFL ALYLSGGVIS TFVSYVFKTA TGRLGPSLGA SGSIMTVLAA VCTKIPEAKL GIVLLPVISF SAGNALKALV ALDIAGLVLG WRFFDHAAHL GGALFGVWYI GYGHELIWRK REPLIKFWHE LRNMSPGRPG PGGGGG
3D Structure
ModBase 3D Structure for Q58EK4
Host
Cell Free Expression
Form/Format
Liquid containing glycerol
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
Storage Buffer
Tris-based buffer, 50% glycerol.
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of parl recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for parl recombinant protein
Transmembrane Protein
Application Notes for parl recombinant protein
This is a recombinant transmembrane protein expressed in a cell-free expression system.
NCBI/Uniprot data below describe general gene information for parl. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001014320.1
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NCBI GenBank Nucleotide #
NM_001014298.1
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UniProt Primary Accession #
Q58EK4
[Other Products]
UniProt Related Accession #
Q58EK4[Other Products]
Molecular Weight
42,409 Da
NCBI Official Full Name
presenilins-associated rhomboid-like protein, mitochondrial
NCBI Official Synonym Full Names
presenilin associated, rhomboid-like a
NCBI Official Symbol
parla [Similar Products]
NCBI Official Synonym Symbols
parl; zgc:112986
[Similar Products]
NCBI Protein Information
presenilins-associated rhomboid-like protein, mitochondrial
UniProt Protein Name
Presenilins-associated rhomboid-like protein, mitochondrial
Protein Family
Presenilins-associated rhomboid-like protein
UniProt Gene Name
parl [Similar Products]
UniProt Entry Name
PARL_DANRE
UniProt Comments for parl
Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of opa1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals ().
Research Articles on parl
1. This study demonistrated that Zebrafish Parla- and Parlb-deficiency affects dopaminergic neuron patterning and embryonic survival.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
