Full Product Name
HDLBP (High Density Lipoprotein Binding Protein, HDL-Binding Protein, HBP, FLJ16432, PRO2900, Vigilin, VGL)
Product Synonym Names
Anti -HDLBP (High Density Lipoprotein Binding Protein, HDL-Binding Protein, HBP, FLJ16432, PRO2900, Vigilin, VGL)
Product Gene Name
anti-HDLBP antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 2; NC_000002.11 (242166679..242255254, complement). Location: 2q37.3
3D Structure
ModBase 3D Structure for Q2HJC8
Species Reactivity
Human, Mouse, Rat
Specificity
Recognizes human HDLBP.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a sterile-filtered liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.
Immunogen
Partial sequence of recombinant full-length protein to human HDLBP
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of anti-HDLBP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-HDLBP antibody
Antibodies; Abs to Lipoproteins
Applications Tested/Suitable for anti-HDLBP antibody
Western Blot (WB)
Application Notes for anti-HDLBP antibody
Suitable for use in Western Blotting.
Dilution: Western Blotting: 1:1000-1:2000
NCBI/Uniprot data below describe general gene information for HDLBP. It may not necessarily be applicable to this product.
UniProt Primary Accession #
Q2HJC8
[Other Products]
UniProt Related Accession #
Q00341; Q2HJC8; Q5HYC5; Q6ZN49; Q6ZS03; Q96CF6; Q9P1C0[Other Products]
Molecular Weight
65,353 Da[Similar Products]
NCBI Official Full Name
HDLBP protein
NCBI Official Synonym Full Names
high density lipoprotein binding protein
NCBI Official Symbol
HDLBP [Similar Products]
NCBI Official Synonym Symbols
HBP; VGL; PRO2900; FLJ16432
[Similar Products]
NCBI Protein Information
vigilin; OTTHUMP00000164572; OTTHUMP00000200288; OTTHUMP00000200289; OTTHUMP00000200290; HDL-binding protein; high density lipoprotein-binding protein
UniProt Protein Name
HDLBP protein
UniProt Gene Name
HDLBP [Similar Products]
UniProt Entry Name
Q2HJC8_HUMAN
NCBI Summary for HDLBP
High density lipoprotein-binding protein, also known as vigilin, is a 110-kD protein that specifically binds HDL molecules and may function in the removal of excess cellular cholesterol.[supplied by OMIM]
UniProt Comments for HDLBP
vigilin: a nuclear and cytoplasmic protein that may play a role in cell sterol metabolism. It may function to protect cells from over-accumulation of cholesterol.
Protein type: Lipid-binding; RNA-binding
Chromosomal Location of Human Ortholog: 2q37.3
Cellular Component: cytoplasm; plasma membrane; nucleus
Molecular Function: protein binding; lipid binding
Biological Process: cholesterol metabolic process; lipid transport
Research Articles on HDLBP
1. identified a competition for binding the 69-nt sequence, through which vigilin and HuR exert opposing effects on c-fms expression, suggesting a role for vigilin in suppression of breast cancer progression
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
