Product Name
Glycine amidinotransferase, mitochondrial (GATM), Recombinant Protein
Full Product Name
Recombinant Bovine Glycine amidinotransferase, mitochondrial (GATM)
Product Gene Name
GATM recombinant protein
[Similar Products]
Product Synonym Gene Name
GATM[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
38-423aa, Full Length of Mature Protein
Sequence
STQAATASSR NSCAADDKAT DPLPKDCPVS SFNEWDPLEE VIVGRAENAC VPPFTVEVKA NTYDKHWPFY QKYGGSYFPK DHLQKAVAEI EEMCNILKME GVTVRRPDPI DWSLKYKTPD FESTGLYGAM PRDILIVVGN EIIEAPMAWR ARFFEYRAYR TIIKDYFRRG AKWTTAPKPT MADELYDQDY PIHSVEDRHK LAAQGKFVTT EFEPCFDAAD FIRAGRDIFV QRSQVTNYMG IEWMRKHLAP DYRVHIVSFK DPNPMHIDAT FNIIGPGLVL SNPDRPCHQI DLFKKAGWTI VTPPTPIIPD DHPLWMSSKW LSMNVLMLDE KRVMVDANEV PIQKMFEKLG ISTIKVSIRN ANSLGGGFHC WTCDVRRRGT LQSYFD
3D Structure
ModBase 3D Structure for Q2HJ74
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of GATM recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
GATM recombinant protein
This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.
NCBI/Uniprot data below describe general gene information for GATM. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001039343.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001045878.1
[Other Products]
UniProt Primary Accession #
Q2HJ74
[Other Products]
UniProt Related Accession #
Q2HJ74[Other Products]
Molecular Weight
48,357 Da
NCBI Official Full Name
glycine amidinotransferase, mitochondrial
NCBI Official Synonym Full Names
glycine amidinotransferase
NCBI Official Symbol
GATM [Similar Products]
NCBI Protein Information
glycine amidinotransferase, mitochondrial
UniProt Protein Name
Glycine amidinotransferase, mitochondrial
UniProt Synonym Protein Names
L-arginine:glycine amidinotransferase; Transamidinase
Protein Family
Glycine amidinotransferase
UniProt Gene Name
GATM [Similar Products]
UniProt Comments for GATM
Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development ().
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.