Full Product Name
Anti-ARMS2 Antibody
Product Gene Name
anti-ARMS2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
OMIM
BX842242 Genomic DNA
Purity/Purification
Affinity Purified
Concentration
100ug/200ul (lot specific)
Storage Buffer
Supplied at 0.5 mg/ml in Tris saline,0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Preparation and Storage
This product is stable for several weeks at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20 degree C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Other Notes
Small volumes of anti-ARMS2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ARMS2 antibody
Western Blot (WB), ELISA (EIA)
NCBI/Uniprot data below describe general gene information for ARMS2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001093137.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001099667.1
[Other Products]
UniProt Secondary Accession #
B2Y7I5[Other Products]
UniProt Related Accession #
P0C7Q2[Other Products]
Molecular Weight
11,437 Da
NCBI Official Full Name
age-related maculopathy susceptibility protein 2
NCBI Official Synonym Full Names
age-related maculopathy susceptibility 2
NCBI Official Symbol
ARMS2 [Similar Products]
NCBI Official Synonym Symbols
ARMD8
[Similar Products]
NCBI Protein Information
age-related maculopathy susceptibility protein 2
UniProt Protein Name
Age-related maculopathy susceptibility protein 2
Protein Family
Age-related maculopathy susceptibility protein
UniProt Gene Name
ARMS2 [Similar Products]
NCBI Summary for ARMS2
This gene encodes a protein that is thought to play a role in diseases in the elderly. Mutations in this gene have been associated with age-related macular degeneration. [provided by RefSeq, Oct 2008]
UniProt Comments for ARMS2
ARMS2: Defects in ARMS2 influence susceptibility to age-related macular degeneration type 8 (ARMD8). ARMD is the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid (known as drusen) that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch's membrane. ARMD is likely to be a mechanistically heterogeneous group of disorders, and the specific disease mechanisms that underlie the vast majority of cases are currently unknown. However, a number of studies have suggested that both genetic and environmental factors are likely to play a role.
Chromosomal Location of Human Ortholog: 10q26.13
Cellular Component: mitochondrion; photoreceptor inner segment
Biological Process: retinal homeostasis
Disease: Macular Degeneration, Age-related, 8
Research Articles on ARMS2
1. Studies indicate that the high-risk allele of the 10q26 locus encompasses three genes, PLEKHA1, ARMS2, and HTRA1 with high linkage disequilibrium.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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