Full Product Name
SSX Polyclonal Antibody
Product Gene Name
anti-SSX antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q16384
Other Notes
Small volumes of anti-SSX antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for SSX. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001265620.1
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NCBI GenBank Nucleotide #
NM_001278691.1
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UniProt Primary Accession #
Q16384
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UniProt Secondary Accession #
Q08AJ2; Q5JQ64; A3KN76[Other Products]
UniProt Related Accession #
Q16384[Other Products]
Molecular Weight
21,931 Da
NCBI Official Full Name
protein SSX1
NCBI Official Synonym Full Names
SSX family member 1
NCBI Official Symbol
SSX1 [Similar Products]
NCBI Official Synonym Symbols
SSRC; CT5.1
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NCBI Protein Information
protein SSX1
UniProt Protein Name
Protein SSX1
UniProt Synonym Protein Names
Cancer/testis antigen 5.1; CT5.1; Synovial sarcoma, X breakpoint 1
UniProt Gene Name
SSX1 [Similar Products]
UniProt Synonym Gene Names
CT5.1 [Similar Products]
NCBI Summary for SSX
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX2 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Jul 2013]
UniProt Comments for SSX
Could act as a modulator of transcription.
Research Articles on SSX
1. Data indicate that the oncogene SS18-SSX1 promotes tumorigenesis by increasing the expression of SHC SH2-domain binding protein 1 (SHCBP1), which normally acts as a tumor promoting factor.
Precautions
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Disclaimer
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