Full Product Name
ACSL6 Antibody
Product Synonym Names
EC 6.2.1.3; fatty-acid-coenzyme A ligase; long-chain 6; LACS 6; long-chain acyl-CoA synthetase 6; long-chain-fatty-acid-CoA ligase 6
Product Gene Name
anti-ACSL6 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9UKU0
Species Reactivity
Human, Mouse, Rat
Specificity
ACSL6 Antibody detects endogenous levels of total ACSL6
Purity/Purification
Immunogen affinity purified
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Immunogen
A synthesized peptide
Preparation and Storage
Store at-20 degree C. Stable for 12 months from date of receipt.
Other Notes
Small volumes of anti-ACSL6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-ACSL6 antibody
Western Blot (WB)
Application Notes for anti-ACSL6 antibody
WB: 1:500-1:1000
Western Blot (WB) of anti-ACSL6 antibody
Western blot analysis of extracts from COLO cells and Jurkat cells, using ACSL6 antibody.
NCBI/Uniprot data below describe general gene information for ACSL6. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001009185.1
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NCBI GenBank Nucleotide #
NM_001009185.2
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UniProt Primary Accession #
Q9UKU0
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UniProt Secondary Accession #
O94924; O95829; Q108M9; Q108N0; Q4G191; Q86TN7; J3KPG3[Other Products]
UniProt Related Accession #
Q9UKU0[Other Products]
NCBI Official Full Name
long-chain-fatty-acid--CoA ligase 6 isoform b
NCBI Official Synonym Full Names
acyl-CoA synthetase long chain family member 6
NCBI Official Symbol
ACSL6 [Similar Products]
NCBI Official Synonym Symbols
ACS2; FACL6; LACS2; LACS5; LACS 6
[Similar Products]
NCBI Protein Information
long-chain-fatty-acid--CoA ligase 6
UniProt Protein Name
Long-chain-fatty-acid--CoA ligase 6
UniProt Synonym Protein Names
Long-chain acyl-CoA synthetase 6; LACS 6
Protein Family
Long-chain-fatty-acid--CoA ligase
UniProt Gene Name
ACSL6 [Similar Products]
UniProt Synonym Gene Names
ACS2; FACL6; KIAA0837; LACS5; LACS 6 [Similar Products]
NCBI Summary for ACSL6
The protein encoded by this gene catalyzes the formation of acyl-CoA from fatty acids, ATP, and CoA, using magnesium as a cofactor. The encoded protein plays a major role in fatty acid metabolism in the brain. Translocations with the ETV6 gene are causes of myelodysplastic syndrome with basophilia, acute myelogenous leukemia with eosinophilia, and acute eosinophilic leukemia. Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2011]
UniProt Comments for ACSL6
Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid.
Research Articles on ACSL6
1. ACSL6 drives acyl-CoA toward lipid synthesis and its downregulation improves mitochondrial biogenesis, respiratory capacity and lipid oxidation
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
