Product Name
6330545A04Rik (RSG1), Polyclonal Antibody
Full Product Name
6330545A04Rik Antibody - N-terminal region
Product Gene Name
anti-RSG1 antibody
[Similar Products]
Product Synonym Gene Name
Gm723; Rsg1; 6330545A04Rik[Similar Products]
Antibody/Peptide Pairs
6330545A04Rik peptide (MBS3242315) is used for blocking the activity of 6330545A04Rik antibody (MBS3217419)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: NRRREFGLLE RPVLPPSVVI DTASYKIFVS GKSGVGKTAL VAKLAGLEVP
3D Structure
ModBase 3D Structure for A2A825
Species Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Yeast, Zebrafish
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Homology
Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 93%; Rat: 100%; Yeast: 83%; Zebrafish: 83%
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse 6330545A04Rik
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-RSG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-RSG1 antibody
This is a rabbit polyclonal antibody against 6330545A04Rik. It was validated on Western Blot
Target Description: 6330545A04Rik has a potential effector of the planar cell polarity signaling pathway. It plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. It is involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia and is more generally involved in exocytosis in secretory cells.
Product Categories/Family for anti-RSG1 antibody
Polyclonal; Signal Transduction; Membrane & Traffic;
Applications Tested/Suitable for anti-RSG1 antibody
Western Blot (WB)
Western Blot (WB) of anti-RSG1 antibody
Host: Rabbit
Target Name: 6330545A04Rik
Sample Type: Mouse Spleen lysates
Antibody Dilution: 1.0ug/ml
NCBI/Uniprot data below describe general gene information for RSG1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001074643
[Other Products]
NCBI GenBank Nucleotide #
NM_001081174
[Other Products]
UniProt Primary Accession #
A2A825
[Other Products]
UniProt Related Accession #
A2A825[Other Products]
NCBI Official Full Name
ciliogenesis and planar polarity effector 2
NCBI Official Synonym Full Names
ciliogenesis and planar polarity effector 2
NCBI Official Symbol
Cplane2 [Similar Products]
NCBI Official Synonym Symbols
Rsg1; Gm723; b2b2804Clo; b2b2827Clo; 6330545A04Rik
[Similar Products]
NCBI Protein Information
ciliogenesis and planar polarity effector 2; REM2- and Rab-like small GTPase 1
UniProt Protein Name
REM2- and Rab-like small GTPase 1
Protein Family
REM2- and Rab-like small GTPase
UniProt Gene Name
Rsg1 [Similar Products]
UniProt Synonym Gene Names
Gm723 [Similar Products]
UniProt Comments for RSG1
Potential effector of the planar cell polarity signaling pathway. Plays a role in targeted membrane trafficking most probably at the level of vesicle fusion with membranes. Involved in cilium biogenesis by regulating the transport of cargo proteins to the basal body and to the apical tips of cilia. More generally involved in exocytosis in secretory cells ().
Research Articles on RSG1
1. RSG1 localizes to the mother centriole in a process that depends on tau tubulin kinase 2 (TTBK2), the CPLANE complex protein Inturned (INTU), and its own GTPase activity. The data suggest a specific role for RSG1 in the final maturation of the mother centriole and ciliary vesicle that allows extension of the ciliary axoneme.
Precautions
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Disclaimer
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