Full Product Name
ApoC2 antibody
Product Synonym Names
Goat polyclonal ApoC2 antibody (IgG fraction); Polyclonal ApoC2 antibody; Anti-ApoC2 antibody; ApoC-2 antibody; ApoC 2 antibody; ApoCII antibody; Apolipoprotein C2 antibody; ApoC II antibody; ApoC-II antibody
Product Gene Name
anti-ApoC2 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P02655
Form/Format
In 10 mM PBS, pH 7.4,0.2 um filtered with 0.05% Sodium Azide
Concentration
5.0 mg/ml (lot specific)
Immunogen
ApoC2 antibody was raised in Goat using purified human Apolipoprotein C-II as the immunogen
Preparation and Storage
Store at 4 degree C or-20 degree C.
Other Notes
Small volumes of anti-ApoC2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ApoC2 antibody
Apolipoprotein C2 or Apolipoprotein C-II is a protein that in humans is encoded by the APOC2 gene. The protein encoded by this gene is secreted in plasma where it is a component of very low density lipoproteins and chylomicrons. This protein activates the enzyme lipoprotein lipase in capillaries[1], which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis.
Product Categories/Family for anti-ApoC2 antibody
Cardiac Markers
Applications Tested/Suitable for anti-ApoC2 antibody
Immunofluorescence (IF)
NCBI/Uniprot data below describe general gene information for ApoC2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000474.2
[Other Products]
NCBI GenBank Nucleotide #
NM_000483.4
[Other Products]
UniProt Primary Accession #
P02655
[Other Products]
UniProt Secondary Accession #
Q9BS39; Q9UDE3; Q9UNK3; C0JYY4[Other Products]
UniProt Related Accession #
P02655[Other Products]
Molecular Weight
11,284 Da
NCBI Official Full Name
apolipoprotein C-II
NCBI Official Synonym Full Names
apolipoprotein C2
NCBI Official Symbol
APOC2 [Similar Products]
NCBI Official Synonym Symbols
APO-CII; APOC-II
[Similar Products]
NCBI Protein Information
apolipoprotein C-II
UniProt Protein Name
Apolipoprotein C-II
UniProt Synonym Protein Names
Apolipoprotein C2
Protein Family
Apolipoprotein
UniProt Gene Name
APOC2 [Similar Products]
UniProt Synonym Gene Names
APC2; Apo-CII; ApoC-II; ProapoC-II [Similar Products]
NCBI Summary for ApoC2
This gene encodes a lipid-binding protein belonging to the apolipoprotein gene family. The protein is secreted in plasma where it is a component of very low density lipoprotein. This protein activates the enzyme lipoprotein lipase, which hydrolyzes triglycerides and thus provides free fatty acids for cells. Mutations in this gene cause hyperlipoproteinemia type IB, characterized by hypertriglyceridemia, xanthomas, and increased risk of pancreatitis and early atherosclerosis. This gene is present in a cluster with other related apolipoprotein genes on chromosome 19. Naturally occurring read-through transcription exists between this gene and the neighboring upstream apolipoprotein C-IV (APOC4) gene. [provided by RefSeq, Mar 2011]
UniProt Comments for ApoC2
Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. In normolipidemic individuals, it is mainly distributed in the HDL, whereas in hypertriglyceridemic individuals, predominantly found in the VLDL and LDL.
Research Articles on ApoC2
1. Triglyceride-raising variant alleles of the APOC2 encoding apo C-II, associated with clinical Cardiovascular endpoints.
Precautions
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Disclaimer
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