Product Name
Guanidinoacetate N-methyltransferase (GAMT), Recombinant Protein
Full Product Name
Recombinant Rat Guanidinoacetate N-methyltransferase
Product Gene Name
GAMT recombinant protein
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
Full Length, 1-236aa
3D Structure
ModBase 3D Structure for P10868
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
20mM Tris-HCl based buffer, pH8.0
Preparation and Storage
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C. Repeated freezing and thawing is not recommended. Store working aliquots at 4 degree C for up to one week.
Other Notes
Small volumes of GAMT recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for GAMT. It may not necessarily be applicable to this product.
NCBI Accession #
P10868.2
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UniProt Primary Accession #
P10868
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UniProt Related Accession #
P10868[Other Products]
NCBI Official Full Name
Guanidinoacetate N-methyltransferase
NCBI Official Synonym Full Names
guanidinoacetate N-methyltransferase
NCBI Official Symbol
Gamt [Similar Products]
NCBI Official Synonym Symbols
GMT
[Similar Products]
NCBI Protein Information
guanidinoacetate N-methyltransferase
UniProt Protein Name
Guanidinoacetate N-methyltransferase
Protein Family
Guanidinoacetate N-methyltransferase
UniProt Gene Name
Gamt [Similar Products]
NCBI Summary for GAMT
catalyzes the last step of creatine biosynthesis [RGD, Feb 2006]
UniProt Comments for GAMT
Converts guanidinoacetate to creatine, using S-adenosylmethionine as the methyl donor. Important in nervous system development.
Research Articles on GAMT
1. 3D organotypic brain cell cultures showed that GAMT deficiency with significant residual enzymatic activity does not lead to creatine deficiency but generates sufficient guanidinoacetate to irreversibly affect developing brain
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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