Product Name
LACRT, Polyclonal Antibody
Popular Item
Full Product Name
LACRT Polyclonal Antibody
Product Gene Name
anti-LACRT antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
MKFTTLLFLA AVAGALVYAE DASSDSTGAD PAQEAGTSKP NEEISGPAEP ASPPETTTTA QETSAAAVQG TAKVTSSRQE LNPLKSIVEK SILLTEQALA
OMIM
AY005150 Genomic DNA
3D Structure
ModBase 3D Structure for Q9GZZ8
Purity/Purification
Affinity Purification
Immunogen
A synthetic peptide of human LACRT
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location
Secreted
Positive Samples
Mouse thymus, Mouse heart
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Other Notes
Small volumes of anti-LACRT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-LACRT antibody
The protein encoded by this gene is highly expressed in the lacrimal glands and localized primarily to secretory granules and secretory fluid. It augments lacrimal acinar cell secretion, promotes ductal cell proliferation, and stimulates signaling through tyrosine phosphorylation and release of calcium.
Product Categories/Family for anti-LACRT antibody
Polyclonal Antibodies
Applications Tested/Suitable for anti-LACRT antibody
Western Blot (WB)
Application Notes for anti-LACRT antibody
WB: 1:500 - 1:2000
Western Blot (WB) of anti-LACRT antibody
Western blot analysis of extracts of various cell lines, using LACRT antibody at 1:3000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (MBS128200) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 90s.
NCBI/Uniprot data below describe general gene information for LACRT. It may not necessarily be applicable to this product.
NCBI Accession #
NP_150593.1
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NCBI GenBank Nucleotide #
NM_033277.1
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UniProt Primary Accession #
Q9GZZ8
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UniProt Related Accession #
Q9GZZ8[Other Products]
Molecular Weight
Calculated: 14kDa
Observed: 14kDa
NCBI Official Full Name
extracellular glycoprotein lacritin
NCBI Official Synonym Full Names
lacritin
NCBI Official Symbol
LACRT [Similar Products]
NCBI Protein Information
extracellular glycoprotein lacritin
UniProt Protein Name
Extracellular glycoprotein lacritin
Protein Family
Extracellular glycoprotein lacritin
UniProt Gene Name
LACRT [Similar Products]
NCBI Summary for LACRT
The protein encoded by this gene is highly expressed in the lacrimal glands and localized primarily to secretory granules and secretory fluid. It augments lacrimal acinar cell secretion, promotes ductal cell proliferation, and stimulates signaling through tyrosine phosphorylation and release of calcium. [provided by RefSeq, Jul 2008]
UniProt Comments for LACRT
Modulates secretion by lacrimal acinar cells.
Research Articles on LACRT
1. Data show increased levels of lysozyme C (LYZ), lacritin (LACRT) and zinc-alpha-2 glycoprotein 1 (AZGP1) in pooled tear fluid sample from Graves' disease (GD) patients with moderate-to-severe Graves' orbitopathy (GO) compared with GD patients without clinical signs of GO.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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