Full Product Name
SSX1 Antibody, HRP conjugated
Product Synonym Names
Protein SSX1; Cancer/testis antigen 5.1; CT5.1; Synovial sarcoma; X breakpoint 1; SSX1
Product Gene Name
anti-SSX1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q16384
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant Human Protein SSX1 protein (112-188AA)
Preservative
0.03% Proclin 300
Constituents
50% Glycerol, 0.01M PBS, pH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-28697 / sc-8816
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-SSX1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-SSX1 antibody
Could act as a modulator of transcription.
Applications Tested/Suitable for anti-SSX1 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for SSX1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001265620.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001278691.1
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UniProt Primary Accession #
Q16384
[Other Products]
UniProt Secondary Accession #
Q08AJ2; Q5JQ64; A3KN76[Other Products]
UniProt Related Accession #
Q16384[Other Products]
Molecular Weight
21,931 Da
NCBI Official Full Name
protein SSX1
NCBI Official Synonym Full Names
SSX family member 1
NCBI Official Symbol
SSX1 [Similar Products]
NCBI Official Synonym Symbols
SSRC; CT5.1
[Similar Products]
NCBI Protein Information
protein SSX1
UniProt Protein Name
Protein SSX1
UniProt Synonym Protein Names
Cancer/testis antigen 5.1; CT5.1; Synovial sarcoma, X breakpoint 1
UniProt Gene Name
SSX1 [Similar Products]
UniProt Synonym Gene Names
CT5.1 [Similar Products]
UniProt Entry Name
SSX1_HUMAN
NCBI Summary for SSX1
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneous humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. This gene, and also the SSX2 and SSX4 family members, have been involved in t(X;18)(p11.2;q11.2) translocations that are characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are likely responsible for transforming activity. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Jul 2013]
UniProt Comments for SSX1
SSX1: Could act as a modulator of transcription. A chromosomal aberration involving SSX1 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency). Belongs to the SSX family.
Protein type: Cancer Testis Antigen (CTA); Oncoprotein
Chromosomal Location of Human Ortholog: Xp11.23
Molecular Function: protein binding; transcription corepressor activity
Disease: Sarcoma, Synovial
Research Articles on SSX1
1. a rare variant of the SS18-SSX1 fusion transcript, which could not be identified by routine procedures for genetic diagnosis, was detected. In addition, 8 missense mutations of cancer-related genes were confirmed
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