Full Product Name
THRB Antibody, HRP conjugated
Product Synonym Names
Thyroid hormone receptor beta; Nuclear receptor subfamily 1 group A member 2; c-erbA-2; c-erbA-beta; THRB; ERBA2; NR1A2; THR1
Product Gene Name
anti-THRB antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P10828
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Immunogen
Recombinant human Thyroid hormone receptor beta protein(1-461aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-34135 / sc-34138 / sc-10822 / sc-10823 / sc-33313 / sc-34132 / sc-33312 / sc-34137 / sc-10824 / sc-67123
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-THRB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-THRB antibody
Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
Applications Tested/Suitable for anti-THRB antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for THRB. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000452.2
[Other Products]
NCBI GenBank Nucleotide #
NM_000461.4
[Other Products]
UniProt Primary Accession #
P10828
[Other Products]
UniProt Secondary Accession #
P37243; Q13986; Q3KP35; Q6WGL2; Q9UD41; B3KU79[Other Products]
UniProt Related Accession #
P10828[Other Products]
Molecular Weight
54,449 Da
NCBI Official Full Name
thyroid hormone receptor beta
NCBI Official Synonym Full Names
thyroid hormone receptor, beta
NCBI Official Symbol
THRB [Similar Products]
NCBI Official Synonym Symbols
GRTH; PRTH; THR1; ERBA2; NR1A2; THRB1; THRB2; C-ERBA-2; C-ERBA-BETA
[Similar Products]
NCBI Protein Information
thyroid hormone receptor beta
UniProt Protein Name
Thyroid hormone receptor beta
UniProt Synonym Protein Names
Nuclear receptor subfamily 1 group A member 2; c-erbA-2; c-erbA-beta
Protein Family
Thyroid hormone receptor
UniProt Gene Name
THRB [Similar Products]
UniProt Synonym Gene Names
ERBA2; NR1A2; THR1 [Similar Products]
UniProt Entry Name
THB_HUMAN
NCBI Summary for THRB
The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the
biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for THRB
Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.
Research Articles on THRB
1. Loss of heterozygosity in THRB and its proximal microsatellite markers may play a role in tumorigenesis and development in invasive breast cancer.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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