Product Name
Gap junction alpha-3 protein (Gja3), Recombinant Protein
Full Product Name
Recombinant Rat Gap junction alpha-3 protein (Gja3), partial
Product Gene Name
Gja3 recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P29414
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Rattus norvegicus (Rat)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Gja3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Gja3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_077352.1
[Other Products]
NCBI GenBank Nucleotide #
NM_024376.2
[Other Products]
UniProt Primary Accession #
P29414
[Other Products]
UniProt Related Accession #
P29414[Other Products]
Molecular Weight
46,013 Da
NCBI Official Full Name
gap junction alpha-3 protein
NCBI Official Synonym Full Names
gap junction protein, alpha 3
NCBI Official Symbol
Gja3 [Similar Products]
NCBI Protein Information
gap junction alpha-3 protein
UniProt Protein Name
Gap junction alpha-3 protein
UniProt Synonym Protein Names
Connexin-46; Cx46
Protein Family
Gap junction alpha-3 protein
UniProt Gene Name
Gja3 [Similar Products]
UniProt Synonym Gene Names
Cxn-46; Cx46 [Similar Products]
NCBI Summary for Gja3
lens gap junction protein; oligomerizes into intercellular channels and functions to exchange low molecular weight metabolites and ions between adjacent cells; induces voltage-gated currents in nonjunctional plasma membrane [RGD, Feb 2006]
UniProt Comments for Gja3
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.
Research Articles on Gja3
1. the role of the charged residues at the end of TM-1 in voltage sensing in Cx26, Cx46, and Cx50.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
