Full Product Name
DNAH1 Antibody, Biotin conjugated
Product Synonym Names
Dynein heavy chain 1; axonemal; Axonemal beta dynein heavy chain 1; Ciliary dynein heavy chain 1; Heat shock regulated protein 1; HSRF-1; hDHC7; DNAH1; DHC7; DNAHC1; KIAA1410
Product Gene Name
anti-DNAH1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9P2D7
Purity/Purification
>95%, Protein G purified
Immunogen
Recombinant human Dynein heavy chain 1, axonemal protein
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-102481 / sc-102482 / sc-102483
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-DNAH1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-DNAH1 antibody
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity).
Applications Tested/Suitable for anti-DNAH1 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for DNAH1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_056327.4
[Other Products]
NCBI GenBank Nucleotide #
NM_015512.4
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UniProt Primary Accession #
Q9P2D7
[Other Products]
UniProt Secondary Accession #
O00436; O15435; O95491; Q6ZU48; Q86YK7; Q8TEJ4; Q92863; Q9H8E6; Q9UFW6; Q9Y4Z7; B0I1R6[Other Products]
UniProt Related Accession #
Q9P2D7[Other Products]
Molecular Weight
360,959 Da
NCBI Official Full Name
dynein heavy chain 1, axonemal
NCBI Official Synonym Full Names
dynein axonemal heavy chain 1
NCBI Official Symbol
DNAH1 [Similar Products]
NCBI Official Synonym Symbols
HL11; HDHC7; HL-11; DNAHC1; HSRF-1; XLHSRF-1
[Similar Products]
NCBI Protein Information
dynein heavy chain 1, axonemal
UniProt Protein Name
Dynein heavy chain 1, axonemal
UniProt Synonym Protein Names
Axonemal beta dynein heavy chain 1; Ciliary dynein heavy chain 1; Heat shock regulated protein 1; HSRF-1; hDHC7
UniProt Gene Name
DNAH1 [Similar Products]
UniProt Synonym Gene Names
DHC7; DNAHC1; KIAA1410; HSRF-1 [Similar Products]
UniProt Entry Name
DYH1_HUMAN
UniProt Comments for DNAH1
DNAH1: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly. Belongs to the dynein heavy chain family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 3p21.1
Biological Process: sperm motility
Research Articles on DNAH1
1. variation in DNAH1 may play a role in primary ciliary dyskinesia
Precautions
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Disclaimer
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