Full Product Name
RPS10 Antibody
Product Gene Name
anti-RPS10 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P46783
Species Reactivity
Human, Mouse, Rat
Concentration
1.0mg/ml (lot specific)
Other Notes
Small volumes of anti-RPS10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-RPS10 antibody
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for RPS10. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001005.1
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NCBI GenBank Nucleotide #
NM_001014.4
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UniProt Primary Accession #
P46783
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UniProt Secondary Accession #
Q5TZC0; B2R4E3[Other Products]
UniProt Related Accession #
P46783[Other Products]
Molecular Weight
18,898 Da
NCBI Official Full Name
40S ribosomal protein S10
NCBI Official Synonym Full Names
ribosomal protein S10
NCBI Official Symbol
RPS10 [Similar Products]
NCBI Official Synonym Symbols
S10; DBA9
[Similar Products]
NCBI Protein Information
40S ribosomal protein S10
UniProt Protein Name
40S ribosomal protein S10
Protein Family
Ribosomal protein
UniProt Gene Name
RPS10 [Similar Products]
NCBI Summary for RPS10
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S10E family of ribosomal proteins. It is located in the cytoplasm. Variable expression of this gene in colorectal cancers compared to adjacent normal tissues has been observed, although no correlation between the level of expression and the severity of the disease has been found. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternate splicing results in multiple transcript variants that encode the same protein. Naturally occurring read-through transcription occurs between this locus and the neighboring locus NUDT3 (nudix (nucleoside diphosphate linked moiety X)-type motif 3).[provided by RefSeq, Feb 2011]
UniProt Comments for RPS10
RPS10: a ribosomal protein of the S10E family. Located in the cytoplasm and nucleus. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This protein is a component of the 40S subunit.
Protein type: Nucleolus; RNA-binding; Ribosomal; Translation
Chromosomal Location of Human Ortholog: 6p21.31
Cellular Component: cytosol; extracellular matrix; focal adhesion; membrane; nucleolus; nucleoplasm
Molecular Function: protein binding; structural constituent of ribosome
Biological Process: mRNA catabolic process, nonsense-mediated decay; ribosomal small subunit assembly and maintenance; rRNA processing; SRP-dependent cotranslational protein targeting to membrane; translation; translational initiation; viral transcription
Disease: Diamond-blackfan Anemia 9
Research Articles on RPS10
1. These results are consistent with a model in which the Nef protein by binding to two components of the 40S small ribosomal subunit, RPS10 and 18S rRNA, and to a lesser extent to tRNAs, could lead to decreased protein synthesis.
Precautions
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