Annexin A1, ELISA Kit

Annexin A1; Annexin I; Annexin-1; Calpactin II; Calpactin-2; Chromobindin-9; Lipocortin I; Phospholipase A2 inhibitory protein; p35; ANXA1; ANX1

For Research Use Only. Not for use in diagnostic procedures.

For long term storage, please store the entire kit at -20 degree C.

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of ANXA1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS2884438 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Annexin A1 (ANXA1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ANXA1. The ELISA analytical biochemical technique of the MBS2884438 kit is based on ANXA1 antibody-ANXA1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ANXA1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ANXA1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

38,952 Da

annexin A1

Annexin A1

ANX1  [Similar Products]

ANXA1_BOVIN

ANXA1: a calcium/phospholipid-binding protein with which promotes membrane fusion and is involved in endocytosis. Has anti-inflammatory properties and inhibits phospholipase A2 activity. Accumulates on internalized vesicles after EGF-stimulated endocytosis, suggesting that it may be required for a late stage in inward vesiculation. Phosphorylated by PKC, EGFR and Chak1. Phosphorylation results in loss of the inhibitory activity. Annexins are a family of structurally related proteins whose common property is calcium-dependent binding to phospholipids. There are at least ten different annexins in mammalian species. Annexins do not contain signal peptides, yet some annexins (A1, A2 and A5) appear to be secreted in a physiologically regulated fashion.

Protein type: Calcium-binding; Lipid-binding

Cellular Component: apical plasma membrane; basolateral plasma membrane; cytoplasmic vesicle membrane; cytosol; early endosome membrane; extracellular space; extrinsic to external side of plasma membrane; lateral plasma membrane; membrane; nucleus; phagocytic cup

Molecular Function: calcium ion binding; calcium-dependent phospholipid binding; phospholipase A2 inhibitor activity

Biological Process: actin cytoskeleton reorganization; adaptive immune response; G-protein signaling, coupled to cyclic nucleotide second messenger; inflammatory response; innate immune response; monocyte chemotaxis; negative regulation of catalytic activity; negative regulation of exocytosis; negative regulation of T-helper 2 cell differentiation; phagocytosis; positive regulation of interleukin-2 production; positive regulation of T cell proliferation; positive regulation of T-helper 1 cell differentiation; regulation of cell shape; regulation of hormone secretion; regulation of inflammatory response; regulation of interleukin-1 production; regulation of leukocyte migration

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