lysosomal trafficking regulator, ELISA Kit

Mouse Lysosomal-trafficking regulator (LYST) ELISA kit; CHS; CHS1; Chediak-Higashi syndrome 1; beige protein; lysosomal trafficking regulator

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of LYST elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9335295 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the lysosomal trafficking regulator (LYST) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing LYST. The ELISA analytical biochemical technique of the MBS9335295 kit is based on LYST antibody-LYST antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect LYST antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, LYST. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

425,287 Da

lysosomal trafficking regulator

lysosomal-trafficking regulator; CHS1 homolog

Lysosomal-trafficking regulator

Bg; Chs1  [Similar Products]

LYST_MOUSE

LYST: May be required for sorting endosomal resident proteins into late multivesicular endosomes by a mechanism involving microtubules. Defects in LYST are the cause of Chediak-Higashi syndrome (CHS). CHS is a rare autosomal recessive disorder characterized by hypopigmentation, severe immunologic deficiency, a bleeding tendency, neurologic abnormalities, abnormal intracellular transport to and from the lysosome, and giant inclusion bodies in a variety of cell types. Most patients die at an early age unless they receive an allogeneic hematopoietic stem cell transplant (SCT). 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Cellular Component: microtubule cytoskeleton; extrinsic to membrane; cell; cytoplasm; endomembrane system; intracellular; cytosol

Molecular Function: phospholipid binding

Biological Process: response to drug; pigment granule organization and biogenesis; secretion of lysosomal enzymes; natural killer cell mediated cytotoxicity; T cell mediated immunity; leukocyte chemotaxis; neutrophil mediated immunity; mast cell secretory granule organization and biogenesis; defense response to protozoan; endosome transport; endosome to lysosome transport via multivesicular body sorting pathway; positive regulation of natural killer cell activation; microtubule-based process; protein transport; pigmentation; lysosome organization and biogenesis; transport; melanosome organization and biogenesis; phospholipid metabolic process; defense response to bacterium; blood coagulation; defense response to virus; phospholipid homeostasis

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