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ECM1, Polyclonal Antibody

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产品名称: ECM1, Polyclonal Antibody
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简单介绍

ECM1, Polyclonal Antibody


ECM1, Polyclonal Antibody  的详细介绍
Product Name

ECM1, Polyclonal Antibody

Full Product Name

ECM1 Antibody, HRP conjugated

Product Synonym Names
Extracellular matrix protein 1; Secretory component p85; ECM1
Product Gene Name

anti-ECM1 antibody

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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OMIM
U68186 mRNA
3D Structure
ModBase 3D Structure for Q16610
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
>95%, Protein G purified
Form/Format
Liquid
Immunogen
Recombinant Human Extracellular matrix protein 1 protein (386-540AA)
Conjugation
HRP
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-ECM1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
anti-ECM1 antibody
Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity.
Product Categories/Family for anti-ECM1 antibody
Tags & Cell Markers; Immunology
Applications Tested/Suitable for anti-ECM1 antibody
ELISA (EIA)
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NCBI/Uniprot data below describe general gene information for ECM1. It may not necessarily be applicable to this product.
NCBI GI #
322302700
NCBI GeneID
1893
NCBI Accession #
NP_001189787.1 [Other Products]
NCBI GenBank Nucleotide #
NM_001202858.1 [Other Products]
UniProt Primary Accession #
Q16610 [Other Products]
UniProt Secondary Accession #
O43266; Q5T5G4; Q5T5G5; Q5T5G6; Q8IZ60; A8K8S0; B4DW49; B4DY60[Other Products]
UniProt Related Accession #
Q16610[Other Products]
Molecular Weight
63,563 Da
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NCBI Official Full Name
extracellular matrix protein 1 isoform 3
NCBI Official Synonym Full Names
extracellular matrix protein 1
NCBI Official Symbol
ECM1  [Similar Products]
NCBI Official Synonym Symbols
URBWD
  [Similar Products]
NCBI Protein Information
extracellular matrix protein 1
UniProt Protein Name
Extracellular matrix protein 1
UniProt Synonym Protein Names
Secretory component p85
Protein Family
Extracellular matrix protein
UniProt Gene Name
ECM1  [Similar Products]
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NCBI Summary for ECM1
This gene encodes a soluble protein that is involved in endochondral bone formation, angiogenesis, and tumor biology. It also interacts with a variety of extracellular and structural proteins, contributing to the maintenance of skin integrity and homeostasis. Mutations in this gene are associated with lipoid proteinosis disorder (also known as hyalinosis cutis et mucosae or Urbach-Wiethe disease) that is characterized by generalized thickening of skin, mucosae and certain viscera. Alternatively spliced transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
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UniProt Comments for ECM1
Involved in endochondral bone formation as negative regulator of bone mineralization. Stimulates the proliferation of endothelial cells and promotes angiogenesis. Inhibits MMP9 proteolytic activity.
Research Articles on ECM1
1. our work has identified a novel function of ECM1 in inhibiting Th17 cell differentiation in the experimental autoimmune encephalomyelitis model
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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