Probable E3 Ubiquitin-Protein Ligase Makorin-3 (MKRN3), ELISA Kit

For Research Use Only. Not for use in diagnostic procedures.

No significant cross-reactivity or interference between this analyte and analogues is observed.

Store all reagents at 2-8 degree C

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.

Small volumes of MKRN3 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9352437 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Probable E3 Ubiquitin-Protein Ligase Makorin-3 (MKRN3) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MKRN3. The ELISA analytical biochemical technique of the MBS9352437 kit is based on MKRN3 antibody-MKRN3 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MKRN3 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MKRN3. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of MKRN3 (hereafter termed "analyte") in undiluted original Bovine body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

55,645 Da

makorin ring finger protein 3

probable E3 ubiquitin-protein ligase makorin-3

Probable E3 ubiquitin-protein ligase makorin-3

D15S9; RNF63; ZNF127  [Similar Products]

MKRN3_HUMAN

The protein encoded by this gene contains a RING (C3HC4) zinc finger motif and several C3H zinc finger motifs. This gene is intronless and imprinted, with expression only from the paternal allele. Disruption of the imprinting at this locus may contribute to Prader-Willi syndrome. An antisense RNA of unknown function has been found overlapping this gene. [provided by RefSeq, Jul 2008]

MKRN3: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

Protein type: Ubiquitin ligase; Ubiquitin conjugating system; EC 6.3.2.-; EC 6.3.2.19

Chromosomal Location of Human Ortholog: 15q11-q13

Cellular Component: ribonucleoprotein complex

Molecular Function: ligase activity; protein binding; zinc ion binding

Biological Process: protein ubiquitination

Disease: Prader-willi Syndrome; Precocious Puberty, Central, 2

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