Full Product Name
IKZF4 Antibody
Product Synonym Names
EOS; ZNFN1A4
Product Gene Name
anti-IKZF4 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9H2S9
Specificity
The antibody detects endogenous levels of total IKZF4 protein.
Purity/Purification
Antigen Affinity Purification
Form/Format
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Concentration
1 mg/ml (lot specific)
Immunogen
Synthetic peptide of human IKZF4
Preparation and Storage
Store at -20 degree C
Other Notes
Small volumes of anti-IKZF4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-IKZF4 antibody
Members of the Ikaros (ZNFN1A1; MIM 603023) family of transcription factors, which includes Eos, are expressed in lymphocytes and are implicated in the control of lymphoid development.
Product Categories/Family for anti-IKZF4 antibody
Total protein Ab
Applications Tested/Suitable for anti-IKZF4 antibody
Immunohistochemistry (IHC)
Application Notes for anti-IKZF4 antibody
Immunohistochemistry: 1:20-1:100
Immunohistochemistry (IHC) of anti-IKZF4 antibody
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using at dilution 1/20.
Immunohistochemistry (IHC) of anti-IKZF4 antibody
Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue using at dilution 1/20.
NCBI/Uniprot data below describe general gene information for IKZF4. It may not necessarily be applicable to this product.
NCBI Accession #
NP_071910.3
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NCBI GenBank Nucleotide #
NM_022465.3
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UniProt Primary Accession #
Q9H2S9
[Other Products]
UniProt Secondary Accession #
Q96JP3[Other Products]
UniProt Related Accession #
Q9H2S9[Other Products]
Molecular Weight
59,671 Da
NCBI Official Full Name
zinc finger protein Eos
NCBI Official Synonym Full Names
IKAROS family zinc finger 4
NCBI Official Symbol
IKZF4 [Similar Products]
NCBI Official Synonym Symbols
EOS; ZNFN1A4
[Similar Products]
NCBI Protein Information
zinc finger protein Eos
UniProt Protein Name
Zinc finger protein Eos
UniProt Synonym Protein Names
Ikaros family zinc finger protein 4
Protein Family
Zinc finger protein
UniProt Gene Name
IKZF4 [Similar Products]
UniProt Synonym Gene Names
KIAA1782; ZNFN1A4 [Similar Products]
UniProt Entry Name
IKZF4_HUMAN
UniProt Comments for IKZF4
IKZF4: DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems. Belongs to the Ikaros C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: C2H2-type zinc finger protein; DNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 12q13
Cellular Component: centrosome; nucleoplasm; nucleus
Molecular Function: transcription factor activity
Biological Process: negative regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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